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Keywords: flavonol
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Articles
Cardioprotective 3′,4′-dihydroxyflavonol attenuation of JNK and p38 MAPK signalling involves CaMKII inhibition
Available to PurchaseNicholas R. Lim, Colleen J. Thomas, Lokugan S. Silva, Yvonne Y. Yeap, Suwan Yap, James R. Bell, Lea M. D. Delbridge, Marie A. Bogoyevitch, Owen L. Woodman, Spencer J. Williams, Clive N. May, Dominic C. H. Ng
Journal:
Biochemical Journal
Biochem J (2013) 456 (2): 149–161.
Published: 08 November 2013
...) injury. The biological activities of flavonols are associated with kinase modulation to alter cell signalling. We thus investigated the effects of DiOHF on the activation of MAPKs (mitogen-activated protein kinases) that regulate the cardiac stress response. In an ovine model of I/R, JNK (c-Jun N...
Includes: Supplementary data
