... generates a C-terminal fragment, which requires sequential digestion by an aminopeptidase to liberate the fluorescent label. The above-mentioned methods are discontinuous and have a low throughput. To overcome this limitation, IQFSs (intramolecularly quenched fluorogenic substrates) for renin have been...

... fluids and cell lysates. The Biochemical Society, London ©2003 2003 cathepsin cysteine protease fluorogenic substrate trypanosome Abbreviations used: Abz, o -aminobenzoic acid; AMC, 7-amino-4-methyl-coumarin; cat K −/− , cathepsin K knockout; CP, cysteine protease; C-4S, chondroitin...

...-mail [email protected] ). 20 3 2003 2 5 2003 6 5 2003 6 5 2003 The Biochemical Society, London ©2003 2003 lysosomal proteinase cysteine protease fluorogenic substrate Abbreviations used: Abz, o -aminobenzoic acid; ACC, 7-amino-4-carbamoylmethylcoumarin; EDDnp...

... should be addressed (e-mail [email protected] ). 29 5 2002 12 8 2002 29 8 2002 29 8 2002 The Biochemical Society, London ©2002 2002 fluorescent peptide fluorogenic substrate proteinase thiol protease Abbreviations used: Abz, o -aminobenzoic acid; Dap(Dnp...