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Keywords: general control non-derepressible 2 (Gcn2)
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Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2
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Journal:
Biochemical Journal
Biochem J (2015) 466 (3): 547–559.
Published: 06 March 2015
... pES128-9. General control non-derepressible 2 (Gcn2) is involved in many biological functions. We found that Gcn1 directly contacts small ribosomal protein (Rps)10 on the ribosome and this is required for maintaining basal Gcn2-activity and efficiently activating Gcn2 under amino acid starvation...