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Keywords: glioblastoma
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Articles
Biochem J (2020) 477 (23): 4675–4688.
Published: 11 December 2020
...César G. Prucca; Ana C. Racca; Fabiola N. Velazquez; Andrés M. Cardozo Gizzi; Lucia Rodríguez Berdini; Beatriz L. Caputto Glioblastoma multiforme is the most aggressive type of tumor of the CNS with an overall survival rate of approximately one year. Since this rate has not changed significantly...
Includes: Supplementary data
Articles
Biochem J (2020) 477 (19): 3899–3910.
Published: 16 October 2020
... and carbidopa, a drug used in treating Parkinson's disease, activated the AhR. In this study, we identified the neuroactive hormone dopamine as an inducer of drug-metabolizing enzymes CYP1A1, CYP1B1, and UGT1A1 in colon and glioblastoma cells and similar results were observed for carbidopa. In contrast...
Includes: Supplementary data
Articles
Biochem J (2020) 477 (12): 2263–2279.
Published: 24 June 2020
...Prashant Deshmukh; Shruti Mathur; Gejo Gangadharan; Gopinatha Krishnappa; Nandakumar Dalavaikodihalli Nanjaiah; Balasundaram Padmanabhan Glioblastoma (GBM) is the most common primary brain malignancy, rarely amenable to treatment with a high recurrence rate. GBM are prone to develop resistance...
Includes: Supplementary data
Articles
Biochem J (2001) 357 (2): 427–435.
Published: 09 July 2001
... low levels of PKB phosphorylation in a glioblastoma sample carrying a mutation in the extreme C-terminus of PTEN compared with tumours carrying phosphatase-inactivating mutations of the enzyme. Our data show that deregulation of PKB is not a universal feature of tumours carrying PTEN mutations...
Articles
Biochem J (2001) 353 (3): 547–553.
Published: 25 January 2001
... with the processing of MT1-MMP to its proteolytically inactive 43kDa fragment in U-87 glioblastoma and HT-1080 fibrosarcoma tumour cell lines; this processing was also preferentially observed within the caveolar fraction. Interestingly, whereas the expression of caveolin 1had no effect on the MT1-MMP-dependent...