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Keywords: glucolipotoxicity
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Biochem J (2016) 473 (4): 487–496.
Published: 09 February 2016
...Jonathan Barlow; Verena Hirschberg Jensen; Martin Jastroch; Charles Affourtit It has been well established that excessive levels of glucose and palmitate lower glucose-stimulated insulin secretion (GSIS) by pancreatic β-cells. This β-cell ‘glucolipotoxicity’ is possibly mediated by mitochondrial...