..., Pinchin, Howard and Ish-Horowicz (1985) Genetics 111 , 463–486; Howard, Ingham and Rushlow (1988) Genes Dev. 2 , 1037–1046], we isolated five candidate genes predicted to encode GSTs (glutathione S-transferases) from the presumed sepia locus (region 66D5 on chromosome 3L ). All cloned and expressed...

...Rungrutai UDOMSINPRASERT; Marie A. BOGOYEVITCH; Albert J. KETTERMAN In mammalian systems, detoxification enzymes of the GST (glutathione S-transferase) family regulate JNK (c-Jun N-terminal kinase) signal transduction by interaction with JNK itself or other proteins upstream in the JNK pathway...

...Irine A. AXARLI; Daniel J. RIGDEN; Nikolaos E. LABROU Cytosolic GSTs (glutathione S-transferases) are a major reserve of high-capacity binding proteins and exhibit ligand-binding properties for a large variety of compounds. In the present study, the binding of two non-substrate anthraquinone dyes...

...Pakorn WINAYANUWATTIKUN; Albert J. KETTERMAN Glutathione S-transferases (GSTs) are dimeric proteins that play a major role in cellular detoxification. The GSTs in mosquito Anopheles dirus species B, an important malaria vector in South East Asia, are of interest because they can play an important...

... monomers in which each domain has some similarity to the Omega class glutathione S -transferases, is a thiol-dependent reductase (designated TDR1) that converts pentavalent antimonials into trivalent antimonials using glutathione as the reductant. The higher abundance of the enzyme in the mammalian stage...

...-a, tumour necrosis factor-a ; TRAIL, TNF-a-related apoptosis-inducing ligand; sTRAIL, soluble TRAIL ; GST, glutathione S-transferase ; NEM, N-ethylmalemide; DTT, dithiothreitol. 1 These authors contributed equally to this work. 2 To whom correspondence should be addressed (e-mail manzoor!kfshrc.edu.sa...