...James W. Robinson; Iryna Leshchyns’ka; Hovik Farghaian; William E. Hughes; Vladimir Sytnyk; Graham G. Neely; Adam R. Cole Glycogen synthase kinase 3 (GSK3) is essential for normal development and function of the central nervous system. It is especially important for regulating neurotransmission...

... compilation © 2013 Biochemical Society 2013 Akt/protein kinase B (Akt/PKB) β-catenin glycogen synthase kinase 3 (GSK3) protein kinase CK1 pyrvinium pamoate Wnt signalling Nearly all aspects of life are controlled by protein phosphorylation, catalysed by protein kinases which give rise...

... synthase kinase 3 (GSK3) mammalian target of rapamycin (mTOR) proline-rich Akt substrate of 40 kDa (PRAS40) Equal amounts of muscle lysates (corresponding to approximately 30 μg of protein) were loaded into each well of a 4–15% polyacrylamide gradient gel (Bio-Rad Laboratories) for protein...

... responses. 1 To whom correspondence should be addressed (email qlei@fudan.edu.cn ). 18 8 2011 10 9 2011 12 9 2011 12 9 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 DNA damage glycogen synthase kinase 3 (GSK3) phosphoinositide 3-kinase...

... for their detection were insufficiently sensitive. glycogen synthase kinase 3 (GSK3) kinase substrate tracking and elucidation (KESTREL) mitogen-activated-protein-kinase-activated protein kinase-2 (MAPKAP-K2) protein kinase B (PKB) serum- and glucocorticoid-induced protein kinase (SGK) The studies...

... puromycin starting from 24 h after transfection, collected at 72 h and lysed or re-plated on fibronectin. cell adhesion cell migration focal adhesion kinase (FAK) glycogen synthase kinase 3 (GSK3) protein phosphatase protein phosphorylation FAK (focal adhesion kinase) is a non-receptor...

... SAPK2a/p38α or SAPK3/p38γ [ 15 ]. 1 To whom correspondence should be addressed (email j.t.c.murray@dundee.ac.uk ). 26 6 2004 24 9 2004 4 10 2004 4 10 2004 The Biochemical Society, London 2004 glycogen synthase kinase 3 (GSK3) n-myc downstream-regulated gene...

... of positive and negative MAPK regulators. In the case of glycogen synthase kinase 3 (GSK3), the presence of a phosphate-binding site allows docking of previously phosphorylated (primed) substrates; this docking site is also required for the mechanism of GSK3 inhibition by phosphorylation. In contrast, non...