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1-8 of 8
Keywords: heart failure
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Articles
Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy
Open AccessJinxi Wang, Grace Ciampa, Dong Zheng, Qian Shi, Biyi Chen, E. Dale Abel, Tianqing Peng, Duane D. Hall, Long-Sheng Song
Journal:
Biochemical Journal
Biochem J (2021) 478 (19): 3539–3553.
Published: 06 October 2021
...Jinxi Wang; Grace Ciampa; Dong Zheng; Qian Shi; Biyi Chen; E. Dale Abel; Tianqing Peng; Duane D. Hall; Long-Sheng Song Calpain proteolysis contributes to the pathogenesis of heart failure but the calpain isoforms responsible and their substrate specificities have not been rigorously defined. One...
Articles
Heart failure and the glutathione cycle: an integrated view
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2020) 477 (17): 3123–3130.
Published: 04 September 2020
...Anand K. Bachhawat; Shambhu Yadav; Ashwin K. Jainarayanan; Pratiksha Dubey Heart failure results from the heart's inability to carryout ventricular contraction and relaxation, and has now become a worldwide problem. During the onset of heart failure, several signatures are observed...
Articles
Metabolic remodeling of cardiomyocytes identified in phosphoinositide-dependent kinase 1-deficient mice
Available to PurchaseChen Li, Yan Niu, Hong Zheng, Congjia Shan, Qinbo Chen, Zhongzhou Yang, Liangcai Zhao, Changwei Yang, Hongchang Gao
Journal:
Biochemical Journal
Biochem J (2019) 476 (13): 1943–1954.
Published: 09 July 2019
...Chen Li; Yan Niu; Hong Zheng; Congjia Shan; Qinbo Chen; Zhongzhou Yang; Liangcai Zhao; Changwei Yang; Hongchang Gao Metabolic remodeling plays an essential role in the pathophysiology of heart failure (HF). Many studies have shown that the disruption of phosphoinositide-dependent protein kinase-1...
Articles
Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes
Open AccessAndrew A. Gibb, Pawel K. Lorkiewicz, Yu-Ting Zheng, Xiang Zhang, Aruni Bhatnagar, Steven P. Jones, Bradford G. Hill
Journal:
Biochemical Journal
Biochem J (2017) 474 (16): 2785–2801.
Published: 07 August 2017
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cardiac hypertrophy glycolysis heart failure metabolomics mitochondria stable isotope All values are mean ± SEM. All comparisons were made to the relevant control group and performed...
Articles
Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2016) 473 (21): 3769–3789.
Published: 27 October 2016
... ( [email protected] ) * These authors contributed equally to this work. 22 4 2016 20 7 2016 3 8 2016 3 8 2016 © 2016 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2016 autophagy cardiomyocytes doxorubicin heart failure...
Includes: Supplementary data
Articles
Regulation of cholinergic activity by the vesicular acetylcholine transporter
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2013) 450 (2): 265–274.
Published: 15 February 2013
... The Authors Journal compilation © 2013 Biochemical Society 2013 Alzheimer’s disease heart failure Parkinson’s disease sepsis synaptic vesicle vascular dementia Cholinergic neurons in the CNS (central nervous system) and in the periphery secrete the neurotransmitter ACh (acetylcholine...
Includes: Multimedia, Supplementary data
Articles
Hypoxia, via stabilization of the hypoxia-inducible factor HIF-1α, is a direct and sufficient stimulus for brain-type natriuretic peptide induction
Available to PurchaseAlexander Weidemann, Bernd Klanke, Michael Wagner, Tilmann Volk, Carsten Willam, Michael S. Wiesener, Kai-Uwe Eckardt, Christina Warnecke
Journal:
Biochemical Journal
Biochem J (2008) 409 (1): 233–242.
Published: 11 December 2007
.... It is induced under a variety of pathophysiological conditions, including decompensated heart failure and myocardial infarction. Since regional hypoxia is a potential common denominator of increased wall stretch and myocardial hypoperfusion, we investigated the direct effects of hypoxia on BNP expression...
Includes: Supplementary data
Articles
Ca 2+ -ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca 2+ -ATPase 2 isoform (SERCA2c)
Available to PurchaseSaoussen Dally, Raymonde Bredoux, Elisabeth Corvazier, Jens P. Andersen, Johannes D. Clausen, Leonard Dode, Mohammed Fanchaouy, Pascal Gelebart, Virginie Monceau, Frederica Del Monte, Judith K. Gwathmey, Roger Hajjar, Chiraz Chaabane, Régis Bobe, Aly Raies, Jocelyne Enouf
Journal:
Biochemical Journal
Biochem J (2006) 395 (2): 249–258.
Published: 28 March 2006
...+ -ATPase isoforms in heart failure. Comparative expression of SERCAs and PMCAs (plasma-membrane Ca 2+ -ATPases) was performed in four nonfailing hearts and five failing hearts displaying mixed cardiomyopathy and idiopathic dilated cardiomyopathies. Relative to normal subjects, cardiomyopathic patients...
Includes: Supplementary data
