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1-7 of 7
Keywords: hepatocellular carcinoma
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Articles
Shawn Lu Wen Tan, Hui Min Tan, Erez Israeli, Indah Fatihah, Vignesh Ramachandran, Shamsia Bte Ali, Shane Jun An Goh, Jillian Wee, Alicia Qian Ler Tan, Wai Leong Tam, Weiping Han
Journal:
Biochemical Journal
Biochem J (2023) 480 (24): 2045–2058.
Published: 18 December 2023
... selective overexpression in multiple cancers and its role in preventing ferroptosis. Utilizing pharmacological and genetic approaches in hepatocellular carcinoma cell lines, we demonstrate that overexpression of SLC7A11 engenders hypersensitivity towards l -selenocystine, a naturally occurring diselenide...
Includes: Supplementary data
Articles
Suzanne Madgwick, Saimir Luli, Helene Sellier, Jacqueline A. Butterworth, Jack Leslie, Adam J. Moore, Emma K. Corbin, Adrian I. Yemm, Robson T. Chiremba, Dina Tiniakos, Fiona Oakley, Neil D. Perkins, Jill E. Hunter
Journal:
Biochemical Journal
Biochem J (2022) 479 (19): 2115–2130.
Published: 14 October 2022
... liver disease. Importantly, we demonstrate a tumour suppressor role for Claspin. Reduced Claspin levels result in increased liver damage and tumourigenesis in the DEN model of hepatocellular carcinoma. These data reveal that Clspn haploinsufficiency has widespread unanticipated biological effects...
Includes: Supplementary data
Articles
In Collection
Towards systems biochemistry
Journal:
Biochemical Journal
Biochem J (2022) 479 (12): 1361–1374.
Published: 24 June 2022
... factors hepatocellular carcinoma hepatocytes liver mathematical modelling Cell-to-cell communication is known since the mid-1800, when Claude Bernard developed the concept of le milieu intérieur , addressing the concept of molecule secretion and action on a distant organ [ 1 , 2 ]. Since...
Articles
Wided Souissi, Arnold Kaloki, Stuart Etherington, Barbara Domanska, Michelle J. West, Neil Crickmore
Journal:
Biochemical Journal
Biochem J (2019) 476 (24): 3805–3816.
Published: 23 December 2019
...), in a humidified atmosphere containing 5% CO 2 at 37°C. The cells were split when they reach 70–80% confluence. hepatocellular carcinoma leukaemia toxicology Bacillus thuringiensis synthesises crystalline parasporal inclusions during sporulation and this salient feature makes...
Articles
Journal:
Biochemical Journal
Biochem J (2011) 438 (2): 349–358.
Published: 12 August 2011
...Zi-Miao Liu; Joseph T. Tseng; Duang-Yang Hong; Huei-Sheng Huang HCC (hepatocellular carcinoma) is among the most common and lethal cancers worldwide with a poor prognosis mainly due to a high recurrence rate and chemotherapy resistance. ATO (arsenic trioxide) is a multi-target drug that has been...
Articles
Ana Paula Pereira Da Silva, Tatiana El-Bacha, Nattascha Kyaw, Reinaldo Sousa Dos Santos, Wagner Seixas Da-Silva, Fabio C. L. Almeida, Andrea T. Da Poian, Antonio Galina
Journal:
Biochemical Journal
Biochem J (2009) 417 (3): 717–726.
Published: 16 January 2009
...Ana Paula Pereira Da Silva; Tatiana El-Bacha; Nattascha Kyaw; Reinaldo Sousa Dos Santos; Wagner Seixas Da-Silva; Fabio C. L. Almeida; Andrea T. Da Poian; Antonio Galina 3-BrPA (3-bromopyruvate) is an alkylating agent with anti-tumoral activity on hepatocellular carcinoma. This compound inhibits...
Articles
Journal:
Biochemical Journal
Biochem J (2008) 411 (2): 379–386.
Published: 27 March 2008
... widely distributed throughout the body. HGF (hepatocyte growth factor) is a pleiotropic cytokine/growth factor involved in the progression of hepatocellular carcinoma. In the present paper, we report the stimulatory effect of HGF on human 5α-R1 transcription in hepatocellular carcinoma cells. Pre...
