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Keywords: histidine-rich loop
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Articles
The histidine-rich loop in the extracellular domain of ZIP4 binds zinc and plays a role in zinc transport
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Journal:
Biochemical Journal
Biochem J (2019) 476 (12): 1791–1803.
Published: 28 June 2019
... shown that ZIP4–ECD is crucial for optimal zinc uptake but the underlying mechanism has not been clarified. In this work, we examined zinc binding to the isolated ZIP4–ECD from Pteropus Alecto (black fruit bat) and located zinc-binding sites with a low micromolar affinity within a histidine-rich loop...
Includes: Supplementary data