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Keywords: horizontal gene transfer
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Biochem J (2016) 473 (8): 1063–1072.
Published: 08 April 2016
... that defend prokaryotes against foreign DNA. In a type I-F CRISPR–Cas system we show that Cas1 is required for adaptation to new threats, and that this protein is characterized by remarkable structural plasticity. adaptation bacteriophages Csy horizontal gene transfer plasmids protein structure...
Includes: Supplementary data
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Biochem J (2007) 401 (2): e5.
Published: 21 December 2006
... mechanisms are so similar. Other than metal chelators, no inhibitors of carboxypeptidases from family M32 are known. However, the principle that a pathogen's ‘Achilles heel’ might be peptidases that have been acquired by horizontal gene transfer is a valid one. An endopeptidase from a family not present...
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