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Keywords: human NKG2D-ligand
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Articles
A GPI anchor explains the unique biological features of the common NKG2D-ligand allele MICA*008
Available to PurchaseOmodele Ashiru, Sheila López-Cobo, Lola Fernández-Messina, Samuel Pontes-Quero, Rachele Pandolfi, Hugh T. Reyburn, Mar Valés-Gómez
Journal:
Biochemical Journal
Biochem J (2013) 454 (2): 295–302.
Published: 09 August 2013
... undergoing GPI modification while the rest is exocytosed, suggesting a new model for MICA*008 release. This is the first report of a GPI-anchored MICA allele. The finding that this modification occurs in both families of human NKG2D ligands, as well as in the murine system, suggests positive pressure...
Includes: Supplementary data