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Keywords: human calcitonin
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Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47–57) and penetratin(43–58)

Rachel TRÉHIN, Hanne M. NIELSEN, Heinz-Georg JAHNKE, Ulrike KRAUSS, Annette G. BECK-SICKINGER, Hans P. MERKLE
Journal: Biochemical Journal
Biochem J (2004) 382 (3): 945–956.
https://doi.org/10.1042/BJ20040238
Published: 07 September 2004
...-terminal CF [5(6)-carboxyfluorescein]-labelled CPP, namely hCT (human calcitonin)-derived sequences, Tat(47–57) and penetratin(43–58), was through Fmoc (fluoren-9-ylmethoxycarbonyl) chemistry. Metabolic degradation kinetics of the tested CPP in contact with three cell-cultured epithelial models, MDCK...
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