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Keywords: indirubin-3′-monoxime
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Articles
A novel small molecule A 2A adenosine receptor agonist, indirubin-3′-monoxime, alleviates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes
Available to PurchaseSaynaz A. Choudhary, Nikita Bora, Dipanjan Banerjee, Leena Arora, Anindhya Sundar Das, Rakesh Yadav, Karl-Norbert Klotz, Durba Pal, Anupam Nath Jha, Suman Dasgupta
Journal:
Biochemical Journal
Biochem J (2019) 476 (16): 2371–2391.
Published: 30 August 2019
.... Recent reports suggest A 2A adenosine receptor (A 2A AR) could be an attractive choice to counteract adipocyte inflammation and insulin resistance. Thus, an effective A 2A AR agonist devoid of any toxicity is highly appealing. Here, we report that indirubin-3′-monoxime (I3M), a derivative...
Includes: Supplementary data
