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1-8 of 8
Keywords: inhibitor of apoptosis (IAP)
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Articles
Eugene Varfolomeev, Anita Izrael-Tomasevic, Kebing Yu, Daisy Bustos, Tatiana Goncharov, Lisa D. Belmont, Alexandre Masselot, Corey E. Bakalarski, Donald S. Kirkpatrick, Domagoj Vucic
Journal:
Biochemical Journal
Biochem J (2015) 466 (1): 45–54.
Published: 06 February 2015
... and represents a fundamental challenge to sustaining clinical efficacy for currently available agents. Inhibitor of apoptosis (IAP) proteins use their ubiquitin E3 ligase activity to promote cancer cell survival by mediating proliferative signalling and blocking cell death in response to diverse stimuli. Using...
Includes: Supplementary data
Articles
Yoshio Nakatani, Torsten Kleffmann, Katrin Linke, Stephen M. Condon, Mark G. Hinds, Catherine L. Day
Journal:
Biochemical Journal
Biochem J (2013) 450 (3): 629–638.
Published: 28 February 2013
[email protected] ). 12 11 2012 19 12 2012 21 12 2012 21 12 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 cross-linking coupled with mass spectrometry analysis inhibitor of apoptosis (IAP) RING ubiquitin X-linked inhibitor of apoptosis (XIAP...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 430 (2): 199–205.
Published: 13 August 2010
[email protected] 3 6 2010 2 7 2010 6 7 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 cancer therapy inhibitor of apoptosis (IAP) mitochondrion nuclear factor κB (NF-κB) survivin Among the regulators of cell death, the Bcl-2 gene family comprises...
Articles
Journal:
Biochemical Journal
Biochem J (2009) 420 (1): 83–91.
Published: 28 April 2009
... under the terms of the Creative Commons Attribution Non-Commercial Licence ( http://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. CD30 inhibitor of apoptosis (IAP...
Includes: Supplementary data
Articles
Stefanie Galbán, Clara Hwang, Julie M. Rumble, Karolyn A. Oetjen, Casey W. Wright, Alain Boudreault, Jon Durkin, John W. Gillard, James B. Jaquith, Stephen J. Morris, Colin S. Duckett
Journal:
Biochemical Journal
Biochem J (2009) 417 (3): 765–771.
Published: 16 January 2009
... for Aegera Therapeutics Inc. 2 To whom correspondence should be addressed (email [email protected] ). 15 8 2008 2 10 2008 14 10 2008 14 10 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 apoptosis caspase inhibitor of apoptosis (IAP) second...
Articles
Gabriel N. Maine, Xicheng Mao, Patricia A. Muller, Christine M. Komarck, Leo W. J. Klomp, Ezra Burstein
Journal:
Biochemical Journal
Biochem J (2009) 417 (2): 601–609.
Published: 23 December 2008
... a critical interface for protein–protein interactions, such as COMMD1–COMMD1 dimer formation and binding to Cul2 (Cullin2), Elongin C and SOCS1 (suppressor of cytokine signalling 1) [ 1 , 3 – 5 ]. copper metabolism Murr1 (mouse U2af1-rs1 region) domain-containing (COMMD) protein inhibitor of apoptosis...
Articles
John W. Blankenship, Eugene Varfolomeev, Tatiana Goncharov, Anna V. Fedorova, Donald S. Kirkpatrick, Anita Izrael-Tomasevic, Lilian Phu, David Arnott, Mariam Aghajan, Kerry Zobel, J. Fernando Bazan, Wayne J. Fairbrother, Kurt Deshayes, Domagoj Vucic
Journal:
Biochemical Journal
Biochem J (2009) 417 (1): 149–165.
Published: 12 December 2008
... ). 15 9 2008 17 10 2008 22 10 2008 22 10 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 cellular inhibitor of apoptosis (c-IAP) E3 ubiquitin ligase inhibitor of apoptosis (IAP) proteasome ubiquitin ubiquitin-associated domain (UBA domain...
Includes: Supplementary data
Articles
Domagoj VUCIC, Matthew C. FRANKLIN, Heidi J. A. WALLWEBER, Kanad DAS, Brendan P. ECKELMAN, Hwain SHIN, Linda O. ELLIOTT, Saloumeh KADKHODAYAN, Kurt DESHAYES, Guy S. SALVESEN, Wayne J. FAIRBROTHER
Journal:
Biochemical Journal
Biochem J (2005) 385 (1): 11–20.
Published: 14 December 2004
... variants are illustrated schematically in Figure 1 (B). apoptosis inhibitor of apoptosis (IAP) melanoma inhibitor of apoptosis (ML-IAP) Smac/DIABLO (second mitochondrial activator of caspases/direct IAP binding protein with low pI) X-linked IAP (XIAP) A PCR product containing amino acids 56...
