... complex involving the IGF-1 receptor, integrin receptors and FAK (focal adhesion kinase) [ 12 ]. This ability of RACK1 raises questions as to whether additional proteins binding to RACK1 can influence the function and specificity of the complex with regard to the intracellular targeting, conformation...

... test was used to determine significance of differences. Averaged data are presented as means±S.E.M. Values of P <0.05 were considered as statistically significant. The β3-subunit was first isolated from the rat pheochromocytoma cell line PC12 [ 9 ]. To study the intracellular targeting of β3...

... retention glycosylation intracellular targeting Nramp1 Slc11a1 subcellular localization Solute carrier family 11 member 1 (Slc11a1, formerly Nramp1) is an extensively glycosylated, integral membrane protein with 12 putative TMDs (transmembrane domains), which is highly conserved across species...

... The Biochemical Society, London ©2004 2004 cAMP-specific phosphodiesterase (PDE4A7) catalytically inactive isoform intracellular targeting phosphodiesterase rolipram Abbreviations used: PBMC, peripheral blood mononuclear cell; PDE, cyclic nucleotide phosphodiesterase; PDE4, cAMP-specific...

... The Biochemical Society, London © 2000 2000 endocrine exocrine intracellular targeting pancreas Biochem. J. (2000) 350, 637 643 (Printed in Great Britain) 637 Targeting of the zymogen-granule protein syncollin in AR42J and AtT-20 cells Alois HODEL and J. Michael EDWARDSON1 Department of Pharmacology...