... 11 2017 7 2 2018 14 2 2018 14 2 2018 coagulation factors endoplasmic reticulum factor VIII glycoprotein secretion hemophilia intracellular trafficking N-glycosylation is one of the most common posttranslational modifications of secreted and membrane proteins...

... ~200-fold. In cells less sensitive to abrin, the A chain localizes to the nucleus by interacting with BASP1, indicating its role in the cellular resistance to abrin. abrin brain acid-soluble protein (BASP) intracellular trafficking nuclear localization ribosome-inactivating proteins...

... displays increased cell-surface levels and no longer responds to insulin [ 21 ]. We hypothesized that N-glycosylation of GLUT4 could be implicated in its intracellular trafficking. For the first time, we have used a combination of physiologically relevant cells (adipocyte and muscle cell models...

... membrane-raft fractions, we show that TβRIII recruits both TβRII and TβRI to non-raft membrane fractions. Immunofluorescence microscopy analysis demonstrated that overexpression of TβRIII affects intracellular trafficking of TβRII by recruiting TβRII to EEA1 (early endosome antigen 1)- and Rab5-positive...

....de ). 24 2 2006 31 3 2006 12 4 2006 The Biochemical Society, London 2006 acylation cycle differential activation intracellular trafficking nitric oxide synthase protein–protein interaction subcellular targeting Small and swift, but certainly not soft...

...Nicolas BAROIS; Oddmund BAKKE The four members of the AP (adaptor protein) family are heterotetrameric cytosolic complexes that are involved in the intracellular trafficking of cargo proteins between different organelles. They interact with motifs present in the cytoplasmic tails of their specific...

... Biosciences). 1 To whom correspondence should be addressed (e-mail [email protected] ). 14 4 2004 27 4 2004 27 4 2004 The Biochemical Society, London 2004 Alzheimer's disease β-amyloid intracellular trafficking presenilin syntaxin 5 Mutations in the genes...

... The Biochemical Society, London ©2003 2003 coiled-coil early endosomes intracellular trafficking PC12 cells Abbreviations used: DTT, dithiothreitol; 2D, two-dimensional; 3D, three-dimensional; GFP, green fluorescent protein; GST, glutathione S-transferase; HCA, hydrophobic cluster analysis; LB...