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Keywords: lactacystin
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Biochem J (2014) 458 (1): 95–107.
Published: 20 January 2014
...-11195 [1-(2-chlorophenyl)- N -methyl- N -(1-methylpropyl)-3-isoquinolinecarboxamide], Rif (rifampicin), Lac (lactacystin), Andro (5α-androstan-3α-ol) and DEHP (di-2-ethylhexyl phthalate) were purchased from Sigma–Aldrich. CITCO {6-(4-chlorophenyl)imidazo[2,1-b][ 1 , 3 ]thiazole-5-carbaldehyde O -(3,4...
Includes: Supplementary data
Biochem J (2003) 375 (3): 663–671.
Published: 01 November 2003
... apoptosis atypical protein kinase C caspase lactacystin proteasome tumour necrosis factor (TNF) Abbreviations used: Ac-DEVDal, acetyl-Asp-Glu-Val-Asp-aldehyde; CAT ζ, catalytic domain of PKC ζ; CHX, cycloheximide; DAG, diacylglycerol; DTT, dithiothreitol; MBP, myelin basic protein; PDK-1...
Biochem J (2001) 353 (3): 493–501.
Published: 25 January 2001
... treatment of HepG2 cells with tunicamycin decreased the net production of apoB-100 by enhancing co-translational degradation of the protein. This effect of tunicamycin was partly prevented by lactacystin, a specific proteasome inhibitor. Because lactacystin only partly reversed the effects of tunicamycin on...
Biochem J (2000) 352 (2): 277–285.
Published: 24 November 2000
... correspondence should be addressed (e-mail shorie-v@pharm.teikyo-u.ac.jp ). 2 6 2000 21 8 2000 15 9 2000 The Biochemical Society, London © 2000 2000 atherosclerosis Factor X lactacystin lysophosphatidic acid Biochem. J. (2000) 352, 277 285 (Printed in Great Britain) 277...
Biochem J (2000) 348 (1): 93–101.
Published: 09 May 2000
...-dependent. In the present study we investigate the activation of JNK and p38 in a single non-neuronal cell type, undergoing receptor-mediated (tumour necrosis factor-related apoptosis-inducing ligand and CD95) or chemically-induced (lactacystin) apoptosis. In Jurkat T-cells, receptor-mediated and chemically...
Biochem J (1999) 340 (1): 127–133.
Published: 10 May 1999
... triggered by Z-LLL-CHO, suggesting that the activation of the GM-CSF signalling pathway can partly overcome the apoptotic effect induced by Z-LLL-CHO. Apoptosis induced by inhibition of the proteasome pathway was verified in studies with lactacystin, a highly specific and irreversible proteasome inhibitor...