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1-4 of 4
Keywords: lactate transport
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Articles
Journal:
Biochemical Journal
Biochem J (2015) 466 (1): 177–188.
Published: 06 February 2015
... the binding site of MCT1 for AR-C155858, a potent and specific inhibitor. Key amino acids within the binding site differ between MCT1 and MCT4 accounting for isoform specificity. lactate transport molecular dynamics (MD) simulations molecular modelling monocarboxylate transporter 1 (MCT1...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 431 (2): 217–225.
Published: 28 September 2010
... of lactate transport by these constructs indicated that embigin modulates MCT2 sensitivity to AR-C155858 through interactions with both the intracellular C-terminus and TMs 3 and 6 of MCT2. The C-terminus of MCT2 was found to be essential for its expression with endogenous basigin. 1 To whom...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 425 (3): 523–530.
Published: 15 January 2010
...Matthew J. Ovens; Andrew J. Davies; Marieangela C. Wilson; Clare M. Murray; Andrew P. Halestrap In the present study we characterize the properties of the potent MCT1 (monocarboxylate transporter 1) inhibitor AR-C155858. Inhibitor titrations of L -lactate transport by MCT1 in rat erythrocytes were...
Includes: Supplementary data
Articles
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes
Available to PurchaseStefan BRÖER, Angelika BRÖER, Hans-Peter SCHNEIDER, Carola STEGEN, Andrew P. HALESTRAP, Joachim W. DEITMER
Journal:
Biochemical Journal
Biochem J (1999) 341 (3): 529–535.
Published: 26 July 1999
...Stefan BRÖER; Angelika BRÖER; Hans-Peter SCHNEIDER; Carola STEGEN; Andrew P. HALESTRAP; Joachim W. DEITMER Observations on lactate transport in brain cells and cardiac myocytes indicate the presence of a high-affinity monocarboxylate transporter. The rat monocarboxylate transporter isoform MCT2...