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Keywords: late endosomeClose
Biochem J (2021) 478 (10): 1959–1976.
Published: 28 May 2021
... late endosomes to form amphisomes. This fusion event allows newly generated autophagosomes to gain retrograde transport motility and move toward the soma, where proteolytically active lysosomes are predominantly located. Amphisomes are not only the products of autophagosome maturation but also the...
Biochem J (2011) 434 (2): 219–231.
Published: 11 February 2011
...Jörg Behnke; Eeva-Liisa Eskelinen; Paul Saftig; Bernd Schröder TMEM192 (transmembrane protein 192) is a novel constituent of late endosomal/lysosomal membranes with four potential transmembrane segments and an unknown function that was initially discovered by organellar proteomics. Subsequently...
Biochem J (2005) 390 (2): 549–561.
Published: 23 August 2005
... isolation of late endocytic vesicles from mouse liver by magnetic chromatography. Late endosomes from Wt (wild-type) and NPC1 mice were found to differ not only in their cholesterol and sphingomyelin content, as expected, but also in their non-esterified (‘free’) fatty acid content, with NPC1 vesicles...
Biochem J (2004) 377 (3): 693–700.
Published: 01 February 2004
... homologues of yeast Snf7p, designated hSnf7-1, hSnf7-2 and hSnf7-3, and a single human Vps20p homologue, designated hVps20, that may have similar roles in humans. Immunofluorescence studies showed that hSnf7-1 and hSnf7-3 localized in large vesicular structures that also co-localized with late endosomal...
Biochem J (2002) 365 (3): 721–730.
Published: 01 August 2002
... microscopy [1,2]. We recently demonstrated  LAPTM4a to be a resident protein of lysosomes and late endosomes by using indirect immunofluorescence microscopic analysis of transiently expressed wild-type LAPTM4a and N-terminal haemagglu- tinin epitope-tagged LAPTM4a in cultured cells. Functional studies...