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Keywords: leucine-rich repeat kinase
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Articles
Biochem J (2020) 477 (7): 1203–1218.
Published: 02 April 2020
...Margaux Leemans; Christian Galicia; Egon Deyaert; Elise Daems; Linda Krause; Jone Paesmans; Els Pardon; Jan Steyaert; Arjan Kortholt; Frank Sobott; Dagmar Klostermeier; Wim Versées Mutations in the Parkinson's disease (PD)-associated protein leucine-rich repeat kinase 2 (LRRK2) commonly lead to a...
Includes: Supplementary data
Articles
Biochem J (2019) 476 (19): 2797–2813.
Published: 11 October 2019
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . centrosome cohesion leucine-rich repeat kinase protein phosphorylation Rab protein Parkinson's disease (PD) is a neurodegenerative disorder which affects ∼1% of people over...
Includes: Supplementary data
Articles
Biochem J (2019) 476 (1): 51–66.
Published: 07 January 2019
... disease-associated protein LRRK2 (leucine-rich repeat kinase 2). We previously demonstrated that the Roco protein from Chlorobium tepidum (CtRoco) undergoes a dimer–monomer cycle during the GTPase reaction, with the protein being mainly dimeric in the nucleotide-free and GDP (guanosine-5′-diphosphate...
Includes: Supplementary data
Articles
Biochem J (2018) 475 (11): 1861–1883.
Published: 06 June 2018
... Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . kinase Leucine-rich repeat kinase Parkinson's disease signalling phosphorylation Rab proteins VPS35 Parkinson's disease (PD) is a common...
Includes: Supplementary data
Articles
Biochem J (2018) 475 (7): 1271–1293.
Published: 09 April 2018
... pharmacodynamic marker for LRRK2 kinase activity. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 kinases leucine-rich repeat kinase Parkinson's disease phosphorylation/dephosphorylation SQSTM1 Correspondence: R. Jeremy Nichols ( jnichols...
Includes: Supplementary data
Articles
Biochem J (2018) 475 (1): 1–22.
Published: 02 January 2018
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . antibodies leucine-rich repeat kinase Parkinson's disease protein kinase Rab GTPases Rab10 Commonly occurring autosomal-dominant missense...
Includes: Supplementary data
Articles
Biochem J (2018) 475 (1): 23–44.
Published: 02 January 2018
...Ying Fan; Andrew J.M. Howden; Adil R. Sarhan; Pawel Lis; Genta Ito; Terina N. Martinez; Kathrin Brockmann; Thomas Gasser; Dario R. Alessi; Esther M. Sammler There is compelling evidence for the role of the leucine-rich repeat kinase 2 (LRRK2) and in particular its kinase function in Parkinson's...
Includes: Supplementary data