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Keyword: lipid
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Articles
Biochem J (2015) 469 (1): 71-82.
Published: 19 June 2015
... present study, we conducted a comprehensive and unbiased metabolomic profiling of liver tissue from AdKO (adiponectin-knockout) mice, with and without adiponectin supplementation, fed on an HFD (high-fat diet) to derive insight into the mechanisms and consequences of insulin resistance. Hepatic lipid...
Includes: Supplementary data
Articles
Biochem J (2015) 465 (1): 79-87.
Published: 12 December 2014
... the removal of lipid-derived aldehydes. However, ALDH3B2 and ALDH3B3 have yet to be characterized. In the present study, we examined the enzyme activity, tissue distribution and subcellular localization of ALDH3B2 and ALDH3B3. Both were found to exhibit broad substrate preferences from medium- to long...
Articles
Biochem J (2015) 465 (1): 127-137.
Published: 12 December 2014
...Penny Beckerson; Michael T. Wilson; Dimitri A. Svistunenko; Brandon J. Reeder Cytoglobin (Cygb) is a hexa-co-ordinate haem protein from the globin superfamily with a physiological function that is unclear. We have previously reported that the haem co-ordination is changed in the presence of lipids...
Articles
Biochem J (2014) 457 (3): 463-472.
Published: 10 January 2014
...Enrico Dainese; Enrico Dainese; Gianni De Fabritiis; Annalaura Sabatucci; Sergio Oddi; Clotilde Beatrice Angelucci; Chiara Di Pancrazio; Toni Giorgino; Nathaniel Stanley; Michele Del Carlo; Benjamin F. Cravatt; Mauro Maccarrone Lipid composition is expected to play an important role in modulating...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2013) 452 (3): 401-410.
Published: 31 May 2013
...Woojin Scott Kim; Jen-Hsiang T. Hsiao; Surabhi Bhatia; Elias N. Glaros; Anthony S. Don; Shuichi Tsuruoka; Cynthia Shannon Weickert; Glenda M. Halliday Members of the ABCA (ATP-binding cassette subfamily A) family are characterized by their ability to transport lipids across cellular membranes and...
Articles
Biochem J (2011) 434 (3): 483-492.
Published: 24 February 2011
... determined its role within the cell. In the present paper, we report that the protein is transformed from hexa-co-ordinate to penta-co-ordinate on binding a lipid molecule. This transformation occurs with the ferric oxidation state of the protein, but not the ferrous state, indicating that this process only...
Includes: Supplementary data
Articles
Biochem J (2010) 430 (1): 1-19.
Published: 28 July 2010
... (email vogel@ucalgary.ca ). 31 3 2010 19 5 2010 24 5 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 acyl carrier protein antibiotic fatty acid biosynthesis lipid protein complex De novo FA (fatty acid) synthesis represents a crucial...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2010) 429 (2): 235-242.
Published: 28 June 2010
... the direct visualization of complex phenomena at the level of the entire organism. This potential is now also being increasingly appreciated by the lipid research community. In the present review we summarize basic information on the lipid composition and distribution in zebrafish tissues, including...
Articles
Biochem J (2010) 425 (1): 215-224.
Published: 14 December 2009
... adipocyte development including the induction of PPARγ (peroxisome-proliferator-activated receptor γ), the generation of an endogenous PPARγ ligand and the expression of several genes critical for lipid biosynthesis. Despite its significance, the regulation of SREBP1c expression during adipogenesis is not...
Includes: Supplementary data
Articles
Biochem J (2009) 423 (1): 1-14.
Published: 14 September 2009
...Matthew A. Churchward; Jens R. Coorssen Exocytosis is a highly conserved and essential process. Although numerous proteins are involved throughout the exocytotic process, the defining membrane fusion step appears to occur through a lipid-dominated mechanism. Here we review and integrate the current...
Articles
Biochem J (2009) 420 (2): 191-201.
Published: 13 May 2009
...Chacko Jobichen; Aaron Z. Fernandis; Adrian Velazquez-Campoy; Ka Yin Leung; Yu-Keung Mok; Markus R. Wenk; J. Sivaraman Lipocalins are a broad family of proteins identified initially in eukaryotes and more recently in Gram-negative bacteria. The functions of lipocalin or lipid-binding proteins are...
Includes: Supplementary data
Articles
Biochem J (2008) 415 (3): 387-399.
Published: 15 October 2008
...Sabine König; Till Ischebeck; Jennifer Lerche; Irene Stenzel; Ingo Heilmann Plants exposed to hyperosmotic stress undergo changes in membrane dynamics and lipid composition to maintain cellular integrity and avoid membrane leakage. Various plant species respond to hyperosmotic stress with transient...
Includes: Supplementary data
Articles
Biochem J (2005) 390 (2): 549-561.
Published: 23 August 2005
... late endosome lipid magnetic isolation Niemann–Pick type C NPC (Niemann–Pick type C) is a rare lipidosis characterized by the accumulation of LDL (low-density lipoprotein)-derived non-esterified cholesterol in the E/L (endosomal/lysosomal) system and a subsequent disruption of cholesterol...
Articles
Biochem J (2005) 386 (1): 47-56.
Published: 08 February 2005
...Jocelyn MÉRÉ; Anne CHAHINIAN; Sutherland K. MACIVER; Abdellatif FATTOUM; Nadir BETTACHE; Yves BENYAMIN; Claude ROUSTAN Gelsolin is a calcium-, pH- and lipid-dependent actin filament severing/capping protein whose main function is to regulate the assembly state of the actin cytoskeleton. Gelsolin is...
Articles
Biochem J (2004) 382 (1): 51-57.
Published: 10 August 2004
... AAO60076. 16 2 2004 12 5 2004 18 5 2004 18 5 2004 The Biochemical Society, London 2004 Chlamydomonas reinhardtii CTP:phosphoethanolamine cytidyltransferase gene expression membrane lipid phosphatidylethanolamine Phosphatidylethanolamine (PE) is a major...
Articles
Biochem J (2000) 350 (1): 1-18.
Published: 09 August 2000
... lipid phosphoinositide phospholipase PI 3-kinase recruitment Biochem. J. (2000) 350, 1 18 (Printed in Great Britain) 1 REVIEW ARTICLE Signal-dependent membrane targeting by pleckstrin homology (PH) domains Mark A. LEMMON1 and Kathryn M. FERGUSON The Johnson Research Foundation and Department of...
Articles
Biochem J (2000) 348 (2): 359-365.
Published: 23 May 2000
... Alzheimer's disease (AD). ApoE isoforms bind directly to Alzheimer's amyloid β (Aβ) peptides both in vitro and in vivo . Recent studies suggest that association of apoE with lipids may modulate its interaction with Aβ. We examined the binding of lipid-associated and delipidated apoE3 and apoE4 isoforms to Aβ...
Articles
Biochem J (2000) 346 (3): 561-576.
Published: 07 March 2000
...Bart VANHAESEBROECK; Dario R. ALESSI Phosphoinositide 3-kinases (PI3Ks) generate specific inositol lipids that have been implicated in the regulation of cell growth, proliferation, survival, differentiation and cytoskeletal changes. One of the best characterized targets of PI3K lipid products is...
Articles
Biochem J (1999) 339 (2): 291-298.
Published: 08 April 1999
... cholinephosphotransferase ethanolaminephosphotransferase lipid membrane phospholipid Biochem. J. (1999) 339, 291 298 (Printed in Great Britain) 291 Cloning and expression of a human choline/ethanolaminephosphotransferase : synthesis of phosphatidylcholine and phosphatidylethanolamine Annette L. HENNEBERRY and...