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1-7 of 7
Keywords: lipid kinase
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Articles
Grace Q. Gong, Glenn R. Masson, Woo-Jeong Lee, James M. J. Dickson, Jackie D. Kendall, Manoj K. Rathinaswamy, Christina M. Buchanan, Martin Middleditch, Brady M. Owen, Julie A. Spicer, Gordon W. Rewcastle, William A. Denny, John E. Burke, Peter R. Shepherd, Roger L. Williams, Jack U. Flanagan
Journal:
Biochemical Journal
Biochem J (2024) 481 (23): 1787–1802.
Published: 28 November 2024
... and the Biochemical Society under a transformative agreement with CAUL. lipid kinase membrane proteins phosphoinositide 3-kinase PIK3CA protein conformation small molecules Class I PI3Ks catalyse the conversion of membrane embedded phosphatidylinositol(4,5)-bisphosphate (PIP 2...
Includes: Supplementary data
Articles
Control of diverse subcellular processes by a single multi-functional lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5) P 2 ]
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2016) 473 (12): 1681–1692.
Published: 10 June 2016
... loss of fidelity. In the present review, we summarize studies that have examined the molecular processes that shape the repertoire of PI(4,5) P 2 pools in diverse eukaryotes. Collectively, these studies indicate a conserved role for lipid kinase isoforms in generating functionally distinct pools of PI...
Articles
Ypp1/YGR198w plays an essential role in phosphoinositide signalling at the plasma membrane
Available to PurchaseChao Zhai, Kuoyu Li, Valentini Markaki, John P. Phelan, Katherine Bowers, Frank T. Cooke, Barry Panaretou
Journal:
Biochemical Journal
Biochem J (2008) 415 (3): 455–466.
Published: 15 October 2008
... 2008 Biochemical Society 2008 lipid kinase phosphoinositide Saccharomyces cerevisiae signalling Stt4 Ypp1 PPIn (polyphosphoinositide) second messengers regulate numerous cellular processes in eukaryotes, including organization of the actin cytoskeleton, vesicle trafficking...
Articles
Diacylglycerol kinases: at the hub of cell signalling
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2008) 409 (1): 1–18.
Published: 11 December 2007
...Isabel Mérida; Antonia Ávila-Flores; Ernesto Merino DGKs (diacylglycerol kinases) are members of a unique and conserved family of intracellular lipid kinases that phosphorylate DAG (diacylglycerol), catalysing its conversion into PA (phosphatidic acid). This reaction leads to attenuation of DAG...
Includes: Multimedia, Supplementary data
Articles
AtPIP5K1, an Arabidopsis thaliana phosphatidylinositol phosphate kinase, synthesizes PtdIns(3,4)P2 and PtdIns(4,5)P2 in vitro and is inhibited by phosphorylation
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2001) 359 (3): 583–589.
Published: 25 October 2001
... kinases (PIPkins). These enzymes form a family of lipid kinases distinct from PtdIns 3-kinases and PtdIns 4-kinases, and are classified into three subfamilies (types I III), depending on their substrate specificity. Type I enzymes are PtdIns4P 5-kinases, type II enzymes are PtdIns5P 4-kinases [17...
Articles
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes
Available to PurchaseStuart M. PITSON, Richard J. D'ANDREA, Lucianne VANDELEUR, Paul A. B. MORETTI, Pu XIA, Jennifer R. GAMBLE, Mathew A. VADAS, Binks W. WATTENBERG
Journal:
Biochemical Journal
Biochem J (2000) 350 (2): 429–441.
Published: 23 August 2000
... properties. In all cases, both the native and recombinant SKs displayed remarkably similar properties, indicating that post-translational modifications are not required for basal activity of human SK. Key words: enzyme activation, lipid kinase, second messenger, sphingosine 1-phosphate. also acts...
Articles
Journal:
Biochemical Journal
Biochem J (1999) 337 (2): 171–177.
Published: 08 January 1999
... ). growth-factor receptor lipid kinase mitogenesis protein kinase Ras Biochem. J. (1999) 337, 171 177 (Printed in Great Britain) 171 Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle : role of pertussis-toxin- sensitive G...
