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Keywords: lipid kinase activity
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Articles

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Open Access
Jonathan H. Clarke, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2013) 454 (1): 49–57.
https://doi.org/10.1042/BJ20130488
Published: 26 July 2013
...Jonathan H. Clarke; Robin F. Irvine Mammals have genes coding for three PI5P4Ks (PtdIns5 P 4-kinases), and these have different cellular localizations, tissue distributions and lipid kinase activities. We describe in the present paper a detailed molecular exploration of human PI5P4Ks α, β and γ...
View articletitled, Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization
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Includes: Supplementary data