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Biochem J (2021) 478 (21): 3847–3867.
Published: 09 November 2021
... to power transport. Here, using the model DASS co-transporter, VcINDY from Vibrio cholerae , we have examined the interplay of the three major interactions that occur during transport: the coupling ion, the substrate, and the lipid environment. Using a series of high-throughput thermostability-based...
Includes: Supplementary data
Agnès Ribes, Antoine Oprescu, Julien Viaud, Karim Hnia, Gaëtan Chicanne, Jean-Marie Xuereb, Sonia Severin, Marie-Pierre Gratacap, Bernard Payrastre
Biochem J (2020) 477 (22): 4327–4342.
Published: 26 November 2020
... greatly expanded these last twenty years. Much progress has been made in understanding the roles and regulations of class I PI3Ks which produce the lipid second messenger phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P 3 ). Selective pharmacological inhibitors and genetic approaches have allowed...
Biochem J (2020) 477 (10): 1983–2006.
Published: 29 May 2020
... and infectivity is largely due to its unique waxy cell envelope, 40% of which comprises complex lipids. Therefore, an understanding of the structure and function of the cell wall lipids is of huge indirect clinical significance. This review provides a synopsis of the cell envelope and the major lipids contained...
Biochem J (2019) 476 (19): 2815–2834.
Published: 11 October 2019
... and binds long-chain polyunsaturated fatty acids in its groove formed from the α1 and α2 domains. To identify the molecular basis of its lipid-binding function, we determined the first crystal structure at 2.49 Å resolution for fatty acid-bound ZAG, where the ligand was the fluorescent 11-(dansylamino...
Biochem J (2019) 476 (18): 2657–2676.
Published: 24 September 2019
..., PlpD-like proteins are present in many bacterial species. We characterized the enzymatic activity, specific lipid binding and oligomeric status of PlpD homologs from Aeromonas hydrophila (a fish pathogen), Burkholderia pseudomallei (a human pathogen) and Ralstonia solanacearum (a plant pathogen...
Includes: Supplementary data
Biochem J (2002) 367 (3): 561–570.
Published: 01 November 2002
... metabolism lipids membrane transporter Abbreviations used: BMIPP, 15-( p -iodophenyl)-3( R , S )-methyl pentadecanoic acid; FA, long-chain fatty acids; FABP, fatty acid binding protein; FABP c , cytoplasmic FABP; H-FABP c , heart-type FABP c ; FABP PM , plasma membrane FABP; FAT, fatty acid...
Harold J. G. MEIJER, Christopher P. BERRIE, Cristiano IURISCI, Nullin DIVECHA, Alan MUSGRAVE, Teun MUNNIK
Biochem J (2001) 360 (2): 491–498.
Published: 26 November 2001
...% was PtdIns3 P and the rest was PtdIns4 P . In seedlings of Vicia faba and suspension-cultured tomato cells, the level of PtdIns5 P was about 18%, indicating that PtdIns5 P is a general plant lipid that represents a significant proportion of the PtdIns P pool. Activating phospholipase C (PLC) signalling...
Biochem J (2001) 355 (3): 545–561.
Published: 24 April 2001
... and lipids, all classes of biomolecules can be analysed, and much excellent work has been done in the fields of carbohydrate and nucleic acid biochemistry. lipids MS peptides proteins Biochem. J. (2001) 355, 545 561 (Printed in Great Britain) 545 REVIEW ARTICLE Electrospray and tandem mass...