... and Neisseriaceae families. A surface receptor comprising an integral outer membrane protein, TbpA (Tf-binding protein A), and a surface-exposed lipoprotein, TbpB (Tf-binding protein B), mediates the iron acquisition process. TbpB is thought to extend from the cell surface for capture of Tf to initiate the process...

... compilation © 2010 Biochemical Society 2010 atherosclerosis inflammation lipoprotein oxidized phospholipid phospholipase platelet-activating factor (PAF) PAF-AH [PAF (platelet-activating factor; 1-O-alkyl-2-acetyl- sn -glycero-3-phosphocholine) acetylhydrolase; also known as PLA 2 G7, LpPLA...

... the nucleus of control CHO cells or SK-N-SH neurons. In contrast, when biotinylated apoE was delivered to recipient cells as a lipidated apoE disc, apoE was detected in the nucleus, suggesting that the lipoprotein complex alters the intracellular degradation or trafficking of apoE. Biotinylated apoE discs...

...Vladimir A. SHATROV; Bernhard BRÜNE Oxidized low-density lipoprotein (oxLDL) affects macrophages and plays a critical role in the development of atherosclerosis. In the present paper, we demonstrate that high concentrations of oxLDL provoked apoptosis of human Mono-Mac-6 cells, which was blocked...

...-terminus of CCP indicated that it is a lipoprotein with a signal peptide for cleavage by signal peptidase II. Expression of the gonococcal CCP in E. coli revealed that it is first synthesized as a pro-apo-cytochrome that is translocated across the cytoplasmic membrane. The signal peptide is cleaved...

...Sara DEAKIN; Ilia LEVIEV; Marie-Claude BRULHART-MEYNET; Richard W. JAMES Accumulating data suggest that paraoxonase-1 (PON1) is a primary determinant of the antioxidant and anti-inflammatory capacities of high-density lipoproteins (HDLs). Variations in HDLs and PON1 have been shown to influence...

...Enkhzol MALCHINKHUU; Koichi SATO; Takeshi MURAKI; Koichi ISHIKAWA; Atsushi KUWABARA; Fumikazu OKAJIMA It has been suggested that lipoproteins in the central nervous system are involved in the regulation of several neural functions independent of cholesterol metabolism as well as those related...

...Joanne M. UPSTON; Andrew C. TERENTIS; Kathryn MORRIS; John F. KEANEY, JR; Roland STOCKER Oxidative modification of low-density lipoproteins in the arterial wall is a key feature of atherogenesis and widely believed to cause and/or accelerate lesion development. Linked to this is the expectation...

...Melania D'ORAZIO; Silvia FOLCARELLI; Francesca MARIANI; Vittorio COLIZZI; Giuseppe ROTILIO; Andrea BATTISTONI The leader sequence of Mycobacterium tuberculosis Cu,Zn superoxide dismutase (Cu,ZnSOD) contains a prokaryotic membrane lipoprotein attachment site. In the present study, we have found...

... with 125 I-labelled lipoprotein lipase bound to authentic cell-surface syndecan. In contrast, the 39kDa receptor-associated protein (RAP), a coated-pit ligand, was more than 80% soluble in cold Triton even after internalization; cellular cholesterol depletion failed to substantially affect...

... fat malabsorption, the mice maintain normal concentrations of plasma lipids and liver-derived apoB 100-containing lipoproteins. We investigated the metabolic mechanisms by which plasma lipid levels are kept normal. De novo lipogenesis (DNL) and cholesterogenesis were measured by mass isotopomer...

...-density lipoproteins. The determination of the atomic structure of the MTP–PDI heterodimer has important implications for the treatment of those forms of hyperlipidaemia associated with the overproduction of very-low-density lipoproteins, which predispose to premature coronary heart disease. To perform...