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Keywords: lymphoma
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Biochem J (2013) 451 (3): 427–437.
Published: 12 April 2013
...-inducible factor 1α) from proteasomal degradation, suggesting that it inhibits the proteasome. The results of the present study indicate that the anti-inflammatory effects of BAY 11-7082, its ability to induce B-cell lymphoma and leukaemic T-cell death and to prevent the recruitment of proteins to sites...
Includes: Supplementary data
Biochem J (2012) 444 (2): e3–e5.
Published: 11 May 2012
...Daniel Kirchhofer; Domagoj Vucic Constitutive NF-κB (nuclear factor κB) activation in B-cell lymphomas relies greatly on the CARMA1 [CARD (caspase recruitment domain)-containing MAGUK (membrane-associated guanylate kinase) 1]–Bcl10–MALT1 (mucosa-associated lymphoid tissue translocation gene 1...
Biochem J (2012) 442 (3): 465–481.
Published: 24 February 2012
... the lymphoid microenvironment, leading to release of leukaemia and lymphoma cells from their protective niche. These encouraging findings have given further momentum to PI3K drug development efforts in both cancer and immune diseases. 1 David Fruman is a scientific advisor to Intellikine, a company...
Includes: Multimedia, Supplementary data
Biochem J (2010) 427 (3): 541–550.
Published: 14 April 2010
... elements contributes to diffuse large B-cell lymphoma. BCL6 expression is therefore tightly regulated in a lineage- and developmental-stage-specific manner, and disruption of normal controls can contribute to lymphomagenesis. In order to discover potential cis -acting control regions we carried out DNase I...
Includes: Supplementary data
Biochem J (2009) 420 (1): 83–91.
Published: 28 April 2009
... receptor-associated factor 2)–c-IAP1 complex to the cytoplasmic domain of the Hodgkin's/anaplastic large-cell lymphoma-associated receptor, CD30, leads to the targeting and degradation of the TRAF2–c-IAP1 heterodimer through a mechanism requiring the RING (really interesting new gene) domain of TRAF2...
Includes: Supplementary data
Biochem J (2007) 405 (3): 489–494.
Published: 13 July 2007
...-cell maturation. Expression of centerin, together with bcl - 6 and GCET2 , constitutes a germinal centre B-cell signature, which is associated with a good prognosis in diffuse large B-cell lymphomas, but the molecular basis for this remains to be elucidated. We report here the cloning, expression...