... of its targets [ 24 ] as well as to be important for proper motility and morphology of mitochondria in yeast [ 23 ]. The partial effect of Puf3p deletion on mRNA localization suggests that there might be redundant systems that could also associate mRNAs to mitochondria. One of these alternative...

...Catherine Martel; Paolo Macchi; Luc Furic; Michael A. Kiebler; Luc Desgroseillers Mammalian Stau1 (Staufen1), a modular protein composed of several dsRBDs (double-stranded RNA-binding domains), is probably involved in mRNA localization. Although Stau1 is mostly described in association...

... To whom correspondence should be addressed (e-mail [email protected] ). 12 2 2002 12 4 2002 16 4 2002 The Biochemical Society, London ©2002 2002 cytoskeleton mRNA localization mRNA transport RNA-binding activity RNA-binding protein Abbreviations...

... RNA cross-talking required for the association of the mRNA with the translational machinery. Key words: mRNA localization, oxidative phosphorylation, translation. not all, of the components of the translational machinery [15,16]. Paradigms of these granules are those containing the b-actin mRNA...

..., which are destined for specific compartments in the cell, is achieved by the presence of signals in their polypeptide chains [1,2], whereas cytosolic proteins can be targeted either by protein signals [3] or by the recently discovered mechanism of mRNA localization [4,5]. To date, the available evidence...