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Keywords: manganese
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Biochem J (2019) 476 (21): 3281–3293.
Published: 11 November 2019
... glycosylation diseases. Defects in TMEM165 are associated with strong Golgi glycosylation abnormalities. Our previous work has shown that TMEM165 rapidly degrades with supraphysiological manganese supplementation. In this paper, we establish a functional link between TMEM165 and SPCA1, the Golgi Ca 2+ /Mn 2+ P...
Includes: Supplementary data
Biochem J (2019) 476 (3): 595–611.
Published: 14 February 2019
... 2019 iron manganese oxidative stress Streptococcus pyogenes superoxide dismutases Trace transition metals are important bacterial nutrients, but can be toxic in excess. The concentration of available metal ions is tightly regulated in the host [ 1 ], particularly for Fe and Zn, which...
Includes: Supplementary data
Biochem J (2018) 475 (13): 2127–2151.
Published: 05 July 2018
... of the far-UV CD spectrum and metal content revealed that the addition of Mn ions to Zn–YlaD changed its secondary structure and that iron was substituted for manganese (Mn). The ylaC gene expression using βGlu activity from P yla : gusA was observed at the late-exponential and early-stationary phase...
Includes: Supplementary data
Biochem J (2017) 474 (9): 1481–1493.
Published: 19 April 2017
...; François Foulquier TMEM165 deficiencies lead to one of the congenital disorders of glycosylation (CDG), a group of inherited diseases where the glycosylation process is altered. We recently demonstrated that the Golgi glycosylation defect due to TMEM165 deficiency resulted from a Golgi manganese...
Includes: Supplementary data
Biochem J (2009) 422 (2): 273–283.
Published: 13 August 2009
... 18 6 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 cation diffusion facilitator iron manganese transition metal vacuole yeast zinc Transition metal ions (Cu +/2+ , Fe 2+ , Zn 2+ , Co 2+ and Mn 2+ ) are essential for all organisms as they serve...
Biochem J (2007) 407 (3): 397–406.
Published: 12 October 2007
...Victoria J. Just; Matthew R. Burrell; Laura Bowater; Iain McRobbie; Clare E. M. Stevenson; David M. Lawson; Stephen Bornemann Oxalate decarboxylase (EC catalyses the conversion of oxalate into carbon dioxide and formate. It requires manganese and, uniquely, dioxygen for catalysis. It forms...
Biochem J (2006) 398 (3): 539–546.
Published: 29 August 2006
... The Biochemical Society, London 2006 DMT1 iron iron response element (IRE) Manganese metal transport tetracycline induction Iron and manganese are required nutrients, but both are potentially toxic (reviewed in [ 1 , 2 ]), therefore they must be carefully managed. DMT1 [divalent metal...
Includes: Supplementary data
Biochem J (2005) 391 (3): 527–539.
Published: 25 October 2005
...@bbsrc.ac.uk ). 2 Present address: Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA, U.S.A. electron paramagnetic resonance (EPR) electron spin-echo envelope modulation (ESEEM) Fe-protein hydrolysis manganese nitrogenase The Fe-protein...
Includes: Supplementary data
Biochem J (2005) 386 (3): 479–487.
Published: 08 March 2005
...Mei YANG; Laran T. JENSEN; Allison J. GARDNER; Valeria C. CULOTTA Manganese is an essential, but potentially toxic, trace metal in biological systems. Overexposure to manganese is known to cause neurological deficits in humans, but the pathways that lead to manganese toxicity are largely unknown...
Biochem J (2005) 385 (1): 225–232.
Published: 14 December 2004
... primers progressively more downstream from C2 until the first in-frame stop codon (TAA) was encountered. bivalent cation Cryptococcus neoformans insect cell intracellular parasite manganese Nramp Cryptococcus neoformans causes one of the most important opportunistic infections...
Biochem J (2002) 362 (2): 253–258.
Published: 22 February 2002
... in the levels of copper and manganese in the brains of scrapie-infected mice prior to the onset of clinical symptoms. Interestingly, we noted a major increase in blood manganese in the early stages of disease. Analysis of purified PrP from the brains of scrapie-infected mice also showed a reduction in copper...
Biochem J (2000) 347 (2): 585–591.
Published: 10 April 2000
...-centred radicals accumulating during LiP catalysis. Key words: autocatalysis, Ca Cb cleavage, manganese, peroxyl radicals, white-rot fungi. used in product formation, such as the Ca Cb cleavage reaction to VAD. Therefore the role of O # was studied extensively, leading us to the novel finding that LiP...
Biochem J (2000) 345 (2): 345–350.
Published: 10 January 2000
... substituted with Gln-142 in manganese-containing SODs (Mn-SODs). In order to clarify the contribution of this exchange of Gln to the metal-specific activity of P. gingivalis SOD, we have prepared a mutant of the enzyme with conversions of Gln-70 to Gly and Ala-142 to Gln. The ratio of the specific activities...