... structures alone. In contrast, combining this approach with a mathematical modeling approach can identify the mechanistics of the phenomena of interest. The development of single-cell technologies has also helped clarify the heterogeneity of the NF-κB response and underlying mechanisms. Here, we review...

..., to reduce jet-lag symptoms via melatonin addition [ 9 ], this is mostly a trial and error empirical approach. Although some advances towards more detailed mathematical models of the mammalian circadian clock have been made [ 10 ], melatonin as an effector is not included. With increasing knowledge...

...Daniel Wüstner Transport of the recycling marker transferrin was analysed in polarized hepatic HepG2 cells using quantitative fluorescence microscopy and mathematical modelling. A detailed map and kinetic model for transport of transferrin in hepatic cells was developed. Fluorescent transferrin...