... lipid-interacting motifs specific for lipids characteristic of the inner plasma membrane leaflet. growth hormone receptor immuno T-cell receptor activation motifs intrinsically disordered protein membrane interaction prolactin receptor signalling The prolactin (PRL) receptor (PRLR...

... immunity membrane interaction Mammalian BDs (β-defensins) are small cationic HDPs (host defence peptides), with a characteristic β-sheet fold, that exert their protective functions at the host–environment interface [ 1 ]. They were initially proposed to act as innate immune system effectors...

... to aggregate in solution of the peptide. In the present study, we have analysed the effects of these structural variations on membrane interactions for human LL-37, rhesus RL-37 and orang-utan LL-37, using several complementary biophysical and biochemical methods. CD and ATR (attenuated total reflection)-FTIR...

... and the heterotetramer A2–S100A10 (but not annexins A1, A4 and A5) interact independently of Ca 2+ with the plasma membrane at pH 6.2 and 6.6. The dimerization of annexin A2 within the annexin A2–S100A10 complex is essential for the pH-dependent membrane interaction at this pH range. The pH-induced membrane binding...

... antimicrobial activity innate immunity lipid metabolism lipid-binding membrane interaction saposin-like protein The primary goal of genome sequencing projects is the assignment of a functional context to mere sequence data. Now, right in the middle of the genomics era, it becomes more and more...

... membrane interaction. 1 To whom correspondence should be addressed (email [email protected] ). 13 4 2004 2 7 2004 19 8 2004 19 8 2004 The Biochemical Society, London 2004 actinoporin amphipathic helix membrane interaction pore-forming toxin Pore...

... should be addressed (e-mail [email protected] ). 17 8 2001 2 1 2002 6 2 2002 The Biochemical Society, London ©2002 2002 membrane interaction phosphatidylinositides subcellular localization Abbreviations used: D273K; site-directed mutant containing the amino acid...