... biosynthesis and suppresses autophagy. TORC2, located primarily at the plasma membrane, plays a major role in maintaining the proper levels and bilayer distribution of all plasma membrane components (sphingolipids, glycerophospholipids, sterols, and integral membrane proteins). This article surveys what we...

...Naomi L. Pollock; James Lloyd; Carlotta Montinaro; Megha Rai; Timothy R. Dafforn ATP-binding cassette (ABC) proteins play important roles in cells as importers and exporters but as membrane proteins they are subject to well-known challenges of isolating pure and stable samples for study. One...

... membrane proteins membranes molecular interactions transport The SLC13 transporter family catalyses the transport of dicarboxylates, such as succinate, the tricarboxylate citrate, and sulfate across the plasma membrane of human cells. The five members of the SLC13 family, NaDC1, NaDC3, NaCT...

... dissociation constant ( K d = 14 700 ± 1100 Tspan8/µm 2 ), one of the highest dissociation constants measured for membrane proteins in live cells. We propose that this high dissociation constant, and thus the short lifetime of the Tetraspanin 8 dimer, is critical for Tetraspanin 8 functioning as a master...

... of Tel Aviv University in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with MALMAD. cryo-electron microscopy electron transfer membrane proteins photosystems plant biology Biological energy conversion relies...

... 2020 15 12 2020 4 1 2021 4 1 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 bioluminescence resonance energy transfer cytochrome p450 heme oxygenase-1 membrane proteins nadph-cytochrome p450 reductase protein...

... membrane proteins peroxin PEX14 transmembrane proteins Leishmania , like other medically important kinetoplastid parasites, have a specialized microbody organelle called a glycosome that is evolutionarily related to peroxisome found in higher eukaryotic cells. Glycosomes compartmentalize...

.... Davydov ( [email protected] ) 5 7 2017 30 8 2017 11 9 2017 13 9 2017 © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 allosteric regulation cytochrome P450 drug metabolism membrane proteins protein–protein...

...) copolymers to extract and purify transmembrane proteins, while retaining their native bilayer environment, overcomes many of the disadvantages associated with conventional detergent-based procedures. This approach has huge potential for the future of membrane protein structural and functional studies...

... membrane proteins oligomerization quaternary structure Whether rhodopsin/opsin exists as monomers or forms oligomers has been a longstanding question and the topic has proven to be controversial, especially after the publication of atomic force microscopy (AFM) images of native murine rod outer...

... facilitation to an interaction with the T-cell receptor (TCR) leading to T-cell inhibition by stabilizing an α-helical conformation in the membrane. biophysics fusion inhibitors immune suppression membrane proteins virus cell interaction The initiation of HIV infection begins with viral entry...

... in the biosynthesis of the key lipid species archaetidylethanolamine (AE) and archaetidylglycerol (AG). archaea ether lipid biosynthesis liquid chromatography–mass spectrometry (LC–MS) membrane proteins Table 2 Oligonucleotide primers used in the present study Introduced restriction sites...

... is probably provided by two small helices, P1 and P2, in the phosphorylation domain, which contact the loop between transmembrane α-helices M6 and M7. Ca 2+ -ATPase Ca 2+ transport membrane proteins sarcoplasmic reticulum skeletal muscle Abbreviations used: A domain, activation domain; N...

... membrane proteins protein degradation reactive oxygen species Biochem. J. (1999) 340, 453 458 (Printed in Great Britain) 453 Relationship between cytochrome P450 catalytic cycling and stability : fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is abolished...