... considered to activate these trafficking steps. Furthermore, we suggest how use of new experimental approaches together with phospho-proteomic data may help to further identify mechanisms for activation of these trafficking processes. glucose transport GLUT4 insulin membrane traffic membrane...

...Peter G. Billcliff; Martin Lowe The specific interaction of phosphoinositides with proteins is critical for a plethora of cellular processes, including cytoskeleton remodelling, mitogenic signalling, ion channel regulation and membrane traffic. The spatiotemporal restriction of different...

... 29 11 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 adaptor protein 1 (AP-1) amphiphysin clathrin coated vesicle liposome membrane traffic Membrane transport through the secretory and endocytic pathways is typically mediated by vesicles formed...

... 2010 26 7 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 endosome Ent3p epsin N-terminal homology (ENTH) membrane traffic soluble N -ethylmaleimide-sensitive fusion protein-attachment protein receptor (SNARE) trans -Golgi network (TGN) Bud...

...) membrane traffic palmitoyl-acyl transferase recycling endosome S-acylated peripheral proteins such as the small G-proteins Ras, Gα subunit, and also the neuronal proteins post-synaptic density protein-95 and GAP-43 (growth-associated protein-43) [ 1 ] are synthesized in the cytosol and then post...

... temperature [ 6 , 7 ]. The growth defect of vti1 - 2 cells was used for a multicopy suppressor screen to identify additional components of these transport pathways. The baker's yeast Saccharomyces cerevisiae is a powerful model to study the molecular mechanism of membrane traffic. Several trafficking...

... and reproduction in any medium, provided the original work is properly cited. brefeldin A (BFA) Exo2 Golgi membrane traffic secretory pathway Shiga toxin (STx) Although much of our knowledge of the secretory pathway comes from genetic or biochemical experiments [ 1 , 2 ], small-molecule...

..., London ©2002 2002 C2 domain C-type tandem C2 protein dense-core vesicle exocytosis membrane traffic Abbreviations used: CAP, adenylate cyclase-associated protein; C-type, C-terminal-type; GFP, green fluorescent protein; GST, glutathione S-transferase; HRP, horseradish peroxidase; LC—MS...

... and receptor signalling. Key words: membrane traffic, phosphoinositide, phospho- inositide 3-kinase, protein domains, recruitment. PtdIns(3,4,5)P $ . PtdIns(3,4,5)P $ is produced upon agonist stimu- lation in mammalian cells and interacts with a number of proteins containing pleckstrin homology (PH) domains...

... functions in signal transduction, membrane vesicle trafficking and cytoskeletal dynamics. 1 To whom correspondence should be sent (e-mail moti.liscovitch@;weizmann.ac.il). The Biochemical Society, London © 2000 2000 membrane traffic phosphatidic acid phospholipase D phospholipid...

... 1999 1 4 1999 27 4 1999 The Biochemical Society, London © 1999 1999 ARF1 ARF6 chimaeras HL60 cells membrane traffic Biochem. J. (1999) 341, 185 192 (Printed in Great Britain) 185 ADP ribosylation factor 1 mutants identify a phospholipase D effector region and reveal...