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Keywords: mesotrypsin
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Articles
Itay Cohen, Olumide Kayode, Alexandra Hockla, Banumathi Sankaran, Derek C. Radisky, Evette S. Radisky, Niv Papo
Journal:
Biochemical Journal
Biochem J (2016) 473 (10): 1329–1341.
Published: 11 May 2016
..., thereby limiting their effectiveness. A compelling therapeutic target is mesotrypsin, a protease up-regulated with tumour progression, associated with poor prognosis, and implicated in tumour growth and progression of many cancers. However, with its unique capability for cleavage and inactivation...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2011) 440 (1): 95–105.
Published: 27 October 2011
...Moh'd A. Salameh; Alexei S. Soares; Alexandra Hockla; Derek C. Radisky; Evette S. Radisky PRSS3 /mesotrypsin is an atypical isoform of trypsin, the up-regulation of which has been implicated in promoting tumour progression. Mesotrypsin inhibitors could potentially provide valuable research tools...
