... Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with EBSCO. alpha-methyl- l -tryptophan liver function metabolic syndrome obesity weight loss Obesity, i.e. a body mass index ≥30 kg/m 2 , is a complex disorder arising from...

... was enabled by the participation of the Texas Tech University Health Sciences Center in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with EBSCO. blood-brain barrier brain EIEE25/DEE25 liver metabolic syndrome NACT...

... and has recently reached epidemic proportions. Obesity is also considered to be primarily responsible for the rising prevalence of metabolic syndrome, defined as the coexistence in the same individual of several risk factors for atherosclerosis, including dyslipidemia, hypertension and hyperglycemia...

... the role of macrophages in these processes will help us to develop therapies against detrimental effects of the metabolic syndrome. 1 To whom correspondence should be addressed (email [email protected] ). 23 9 2011 15 11 2011 16 11 2011 © The Authors Journal compilation ©...

... Journal compilation © 2011 Biochemical Society 2011 endoplasmic reticulum (ER) stress insulin resistance metabolic syndrome obesity protein tyrosine phosphatase 1B (PTP1B) ER (endoplasmic reticulum) is a eukaryotic intracellular organelle required for synthesis and metabolism of many...

...). adipocyte differentiation farnesyl pyrophosphate (FPP) ligand metabolic syndrome mevalonate metabolite peroxisome-proliferator-activated receptor γ (PPARγ) The pathophysiology of obesity and obesity-associated metabolic disorders including Type 2 diabetes mellitus, hypertension, hyperlipidaemia...

... trials Lancet 2010 375 735 742 1 email [email protected] 6 6 2011 17 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 adipocyte differentiation farnesyl pyrophosphate (FPP) ligand metabolic syndrome mevalonate metabolite...

... diabetes metabolic syndrome metabolism obesity Wnt signalling The name Wnt is derived from a combination of two homologous genes; W g (the Drosophila wingless gene) and I nt [the murine homologue MMTV (mouse mammary tumour virus) integration site 1 gene]. Wnts represent a large morphogenic...

... and a unique model for studying its many physiological roles. In addition, it improves the metabolic status of rodents with a metabolic syndrome phenotype, as does treatment with AMPK-activating agents; it is therefore tempting to attribute the therapeutic benefits of regular physical activity to activation...

... 2007 21 11 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 adipokine adiponectin insulin sensitivity metabolic syndrome obesity Although once thought to be an inert energy-storage depot, adipose tissue is now recognized as a major endocrine organ...

... metabolism LKB1 metabolic syndrome AMPK (AMP-activated protein kinase) is the downstream component of a protein kinase cascade that plays a key role in energy homoeostasis [ 1 , 2 ]. AMPK is a heterotrimeric complex of a catalytic subunit (α) and two regulatory subunits (β and γ). Isoforms of all...