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Keywords: metabolomics
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Biochem J (2021) 478 (20): 3685–3721.
Published: 21 October 2021
... by the participation of University of Liverpool in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. flux host metabolomics optimisation proteomics transcriptomics Much of microbial biotechnology consists...
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Biochem J (2019) 476 (13): 1943–1954.
Published: 09 July 2019
... (PDK1) caused severe and lethal HF; however, the metabolic pattern of PDK1 deletion remains ambiguous. 1 H nuclear magnetic resonance-based metabolomics was applied to explore the altered metabolic pattern in Pdk1- deficient mice. Principle component analysis showed significant separation as early as 4...
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Biochem J (2018) 475 (10): 1789–1791.
Published: 31 May 2018
... of conditions underlying metabolic syndrome is still inadequate. In a recent paper published in the Biochemical Journal [ Biochem. J. (2018) 475, 1019–1035], Candi et al. address this lack of knowledge, performing high-throughput metabolomics analysis of visceral fat isolated from obese individuals...
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Biochem J (2017) 474 (16): 2785–2801.
Published: 07 August 2017
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cardiac hypertrophy glycolysis heart failure metabolomics mitochondria stable isotope All values are mean ± SEM. All comparisons were made to the relevant control group and performed...
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Biochem J (2016) 473 (21): 3871–3888.
Published: 27 October 2016
...). † Mean CGG expansion ± SD = 31 ± 5 and 103 ± 40, respectively, for controls and carriers ( P  ≤ 0.0001). ‡ Female-to-male ratio = 1.3 and 1.1, respectively, for the control and premutation groups ( χ 2 P  = 0.802). The protocol for plasma metabolomics was reported in detail recently [ 30...
Includes: Supplementary data
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Biochem J (2016) 473 (14): 2187–2203.
Published: 12 July 2016
... understood. In the present study we used a multiplatform [LC/MS, GC/MS and capillary electrophoresis/MS (CE/MS)], metabolomics, untargeted approach to investigate the metabolic alteration underlying the inequalities observed in obesity-derived ASCs. The metabolic fingerprint (metabolites within the cells...
Includes: Supplementary data
Articles
Biochem J (2012) 444 (2): 333–341.
Published: 11 May 2012
... the catabolism of this compound in perfused rat livers. Using a combination of metabolomics and mass isotopomer analysis, we showed that GHB is metabolized by multiple processes, in addition to its previously reported metabolism in the citric acid cycle via oxidation to succinate. A substrate cycle operates...
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Articles
Biochem J (2008) 409 (1): 27–41.
Published: 11 December 2007
... to further our understanding of network regulation. Arabidopsis metabolic control metabolic flux metabolomics plant metabolic network subcellular compartmentation 1 To whom correspondence should be addressed (email [email protected] ). 14 8 2007 11 9 2007 14...
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Biochem J (2006) 399 (2): 231–239.
Published: 27 September 2006
... demonstrated in a large number of fungal species, and it was proposed that they formed an enzymic cycle [ 15 ]. While this theory has been disputed [ 16 ], there is growing evidence that this cycle does exist, but is awaiting positive proof [ 8 ]. mannitol metabolomics primary fungal metabolism...
Includes: Supplementary data
Articles
Biochem J (2005) 388 (2): 669–677.
Published: 24 May 2005
... derivatization method for metabolome analysis of yeast, coupled to data-mining software that achieve comparable throughput, effort and cost compared with DNA arrays. Our sample workup method enables simultaneous metabolite measurements throughout central carbon metabolism and amino acid biosynthesis, using...