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Keywords: metalloporphyrin
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1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide
Available to PurchaseShasi V. KALIVENDI, Srigiridhar KOTAMRAJU, Sonya CUNNINGHAM, Tiesong SHANG, Cecilia J. HILLARD, B. KALYANARAMAN
Journal:
Biochemical Journal
Biochem J (2003) 371 (1): 151–164.
Published: 01 April 2003
... after treatment of cells. Pre-treatment of CGNs and neuroblastoma cells with the metalloporphyrin antioxidant enzyme mimic, Fe(III)tetrakis(4-benzoic acid)porphyrin (FeTBAP), completely prevented the MPP + -induced caspase 3 activity as did overexpression of glutathione peroxidase (GPx1) and pre...