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Keywords: metals
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Articles

Scutellarin inhibits the uninduced and metal-induced aggregation of α-Synuclein and disaggregates preformed fibrils: implications for Parkinson's disease

Fatima Kamal Zaidi, Shashank Deep
Journal: Biochemical Journal
Biochem J (2020) 477 (3): 645–670.
https://doi.org/10.1042/BCJ20190705
Published: 11 February 2020
...Fatima Kamal Zaidi; Shashank Deep The aggregation of the protein alpha synuclein (α-Syn), a known contributor in Parkinson's disease (PD) pathogenesis is triggered by transition metal ions through occupational exposure and disrupted metal ion homeostasis. Naturally occurring small molecules...
View article titled, Scutellarin inhibits the uninduced and <span class="search-highlight">metal</span>-induced aggregation of α-Synuclein and disaggregates preformed fibrils: implications for Parkinson&#x27;s disease
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Includes: Supplementary data
Articles

Ferritin expression modulates cell cycle dynamics and cell responsiveness to H-ras-induced growth via expansion of the labile iron pool

Or KAKHLON, Yosef GRUENBAUM, Z. Ioav CABANTCHIK
Journal: Biochemical Journal
Biochem J (2002) 363 (3): 431–436.
https://doi.org/10.1042/bj3630431
Published: 24 April 2002
... Pathways Laboratory, Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, U.K. 12 2 2002 1 3 2002 11 3 2002 The Biochemical Society, London ©2002 2002 antisense metals oncogenes Abbreviations used: FT, ferritin; H-FT, heavy ferritin chain; L-FT, light...
View article titled, Ferritin expression modulates cell cycle dynamics and cell responsiveness to H-ras-induced growth via expansion of the labile iron pool
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Articles

The distinct methods by which manganese and iron regulate the Nramp transporters in yeast

Matthew E. PORTNOY, Laran T. JENSEN, Valeria Cizewski CULOTTA
Journal: Biochemical Journal
Biochem J (2002) 362 (1): 119–124.
https://doi.org/10.1042/bj3620119
Published: 08 February 2002
...Matthew E. PORTNOY; Laran T. JENSEN; Valeria Cizewski CULOTTA The bakers yeast Saccharomyces cerevisiae expresses three Smf metal transport proteins that are differentially regulated by metal ions. Smf1p and Smf2p are regulated at the post-translational level by manganese, whereas Smf3p...
View article titled, The distinct methods by which manganese and iron regulate the Nramp transporters in yeast
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