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Keywords: methionine aminopeptidase
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Biochem J (2019) 476 (6): 991–1003.
Published: 22 March 2019
... covalently modify the conserved histidine in Type 2 methionine aminopeptidases (MetAPs) at nanomolar concentrations. Even though a similar mechanism is possible in Type 1 human MetAP, it is inhibited only at millimolar concentration. In this study, we have discovered two Type 1 wild-type MetAPs...
Includes: Multimedia, Supplementary data
Biochem J (2007) 407 (1): e1.
Published: 12 September 2007
... that this methodology provides a comprehensive map of constitutive trimming events mediated by regulatory proteases such as methionine aminopeptidase. This study also identifies previously uncharacterized processing events that highlight potential novel regulatory mechanisms mediated by proteolysis...