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Keywords: mitochondrial biogenesis
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Biochem J (2023) 480 (13): 909–919.
Published: 04 July 2023
... fission/fusion metabolic sensing mitochondrial biogenesis mitochondrial functions Physiological fitness is dictated by the ability to respond to environmental inputs or lifestyle changes. Even though lifestyle changes can be vastly different or ill-defined, decades of work have highlighted...
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Biochem J (2022) 479 (4): 525–536.
Published: 23 February 2022
..., and cancer. Mitochondrial homeostasis is controlled by a triad of mitochondrial biogenesis, dynamics (fusion and fission), and autophagy (mitophagy). Studies have underscored FoxO transcription factors as key mitochondrial regulators. Specifically, FoxOs regulate mitochondrial biogenesis by dampening NRF1...
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Biochem J (2014) 462 (2): 359–371.
Published: 07 August 2014
.... However, blood lactate levels were elevated and Surf1 −/− mice had reduced running endurance, suggesting compromised mitochondrial energy metabolism in vivo . Decreased COX activity in Surf1 −/− mice is associated with increased markers of mitochondrial biogenesis [PGC-1α (peroxisome-proliferator...
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Biochem J (2007) 404 (3): 499–507.
Published: 29 May 2007
... compared with wild-type mice, suggesting that mitochondrial biogenesis was perturbed. However, inhibition of J O 2 by AICA riboside was still present in the mutant mice and thus was clearly not mediated by AMPK. In permeabilized hepatocytes, this inhibition was no longer evident, suggesting that it could...
Includes: Supplementary data
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