... inhibitors. agricultural diseases alternative oxidase di-iron carboxylate proteins mitochondrial diseases pathogens respiratory chain Enzymes act as catalysts for chemical reactions and thereby enable living organisms to adopt to their environment and convert energy from nutrients ready...

... of the stability of the mitochondrial genome and their implications. Correspondence: Sathees C. Raghavan ([email protected]) base excision repair double-strand breaks homologous recombination microhomology-mediated end joining mitochondrial diseases nonhomologous end joining Figure 1...

... and unable to synthesize ATP. Unless otherwise indicated, chemicals of the highest purity were obtained from Sigma–Aldrich. ATP synthase cytochrome c oxidase mitochondrial diseases mtDNA MT-ATP6 mutation oxidative phosphorylation threshold effect Mitochondrial diseases due...

...Rodrigue ROSSIGNOL; Benjamin FAUSTIN; Christophe ROCHER; Monique MALGAT; Jean-Pierre MAZAT; Thierry LETELLIER The study of mitochondrial diseases has revealed dramatic variability in the phenotypic presentation of mitochondrial genetic defects. To attempt to understand this variability, different...

... these findings in relation to the involvement of complex I in mitochondrial diseases. 1 To whom correspondence should be addressed, at Instituto de Biologia Molecular e Celular ( [email protected] ). 11 2 1999 7 5 1999 6 7 1999 The Biochemical Society, London © 1999 1999...

..., London © 1999 1999 cytofluorimetry mitochondrial diseases OXPHOS (oxidative phosphorylation) TMRM (tetramethylrhodamine methyl ester) Biochem. J. (1999) 342, 537 544 (Printed in Great Britain) 537 Defective kinetics of cytochrome c oxidase and alteration of mitochondrial membrane potential...