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Keywords: mosquito
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Articles

Two insulin-like peptides differentially regulate malaria parasite infection in the mosquito through effects on intermediary metabolism

Jose E. Pietri, Nazzy Pakpour, Eleonora Napoli, Gyu Song, Eduardo Pietri, Rashaun Potts, Kong W. Cheung, Gregory Walker, Michael A. Riehle, Hannah Starcevich, Cecilia Giulivi, Edwin E. Lewis, Shirley Luckhart
Journal: Biochemical Journal
Biochem J (2016) 473 (20): 3487–3503.
https://doi.org/10.1042/BCJ20160271
Published: 11 October 2016
... with these studies, we previously showed that knockdown of either of two closely related, infection-induced ILPs, ILP3 and ILP4, in the mosquito Anopheles stephensi decreased infection with the human malaria parasite Plasmodium falciparum through kinetically distinct effects on parasite death. However, the precise...
View article titled, Two insulin-like peptides differentially regulate malaria parasite infection in the <span class="search-highlight">mosquito</span> through effects on intermediary metabolism
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Includes: Supplementary data
Articles

The central role of mosquito cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling

Alexia Chandor-Proust, Jaclyn Bibby, Myriam Régent-Kloeckner, Jessica Roux, Emilie Guittard-Crilat, Rodolphe Poupardin, Muhammad Asam Riaz, Mark Paine, Chantal Dauphin-Villemant, Stéphane Reynaud, Jean-Philippe David
Journal: Biochemical Journal
Biochem J (2013) 455 (1): 75–85.
https://doi.org/10.1042/BJ20130577
Published: 13 September 2013
...Alexia Chandor-Proust; Jaclyn Bibby; Myriam Régent-Kloeckner; Jessica Roux; Emilie Guittard-Crilat; Rodolphe Poupardin; Muhammad Asam Riaz; Mark Paine; Chantal Dauphin-Villemant; Stéphane Reynaud; Jean-Philippe David The resistance of mosquitoes to chemical insecticides is threatening vector...
View article titled, The central role of <span class="search-highlight">mosquito</span> cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling
Open the PDF for The central role of <span class="search-highlight">mosquito</span> cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling in another window
Includes: Supplementary data
Articles

Metabolic pathways in Anopheles stephensi mitochondria

Cecilia Giulivi, Catherine Ross-Inta, Ashley A. Horton, Shirley Luckhart
Journal: Biochemical Journal
Biochem J (2008) 415 (2): 309–316.
https://doi.org/10.1042/BJ20080973
Published: 25 September 2008
...Cecilia Giulivi; Catherine Ross-Inta; Ashley A. Horton; Shirley Luckhart No studies have been performed on the mitochondria of malaria vector mosquitoes. This information would be valuable in understanding mosquito aging and detoxification of insecticides, two parameters that have a significant...
View article titled, Metabolic pathways in Anopheles stephensi mitochondria
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Articles

Evolution of two alanine glyoxylate aminotransferases in mosquito

Qian Han, Seong Ryul Kim, Haizhen Ding, Jianyong Li
Journal: Biochemical Journal
Biochem J (2006) 397 (3): 473–481.
https://doi.org/10.1042/BJ20060469
Published: 13 July 2006
...Qian Han; Seong Ryul Kim; Haizhen Ding; Jianyong Li In the mosquito, transamination of 3-HK (3-hydroxykynurenine) to XA (xanthurenic acid) is catalysed by an AGT (alanine glyoxylate aminotransferase) and is the major branch pathway of tryptophan metabolism. Interestingly, malaria parasites hijack...
View article titled, Evolution of two alanine glyoxylate aminotransferases in <span class="search-highlight">mosquito</span>
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Articles

The structural roles of a conserved small hydrophobic core in the active site and an ionic bridge in domain I of Delta class glutathione S-transferase

Ardcharaporn Vararattanavech, Peerada Prommeenate, Albert J. Ketterman
Journal: Biochemical Journal
Biochem J (2006) 393 (1): 89–95.
https://doi.org/10.1042/BJ20050555
Published: 12 December 2005
...Ardcharaporn Vararattanavech; Peerada Prommeenate; Albert J. Ketterman GSTs (glutathione S-transferases; E.C.2.5.1.18) are a supergene family of dimeric multifunctional enzymes that have a major role in detoxification pathways. Using a GST from the mosquito Anopheles dirus (adGSTD4-4), we have...
View article titled, The structural roles of a conserved small hydrophobic core in the active site and an ionic bridge in domain I of Delta class glutathione S-transferase
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Articles

Reciprocal regulation of glutathione S-transferase spliceforms and the Drosophila c-Jun N-terminal kinase pathway components

Rungrutai UDOMSINPRASERT, Marie A. BOGOYEVITCH, Albert J. KETTERMAN
Journal: Biochemical Journal
Biochem J (2004) 383 (3): 483–490.
https://doi.org/10.1042/BJ20040519
Published: 26 October 2004
... that participates in cell death [ 18 ]. c-Jun N-terminal kinase (JNK) Drosophila glutathione S-transferase hemipterous (HEP; MKK7) JNK activity regulation mosquito GSTs (glutathione S-transferases; EC 2.5.1.18) are a superfamily of multifunctional enzymes involved in normal cellular...
View article titled, Reciprocal regulation of glutathione S-transferase spliceforms and the Drosophila c-Jun N-terminal kinase pathway components
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Articles

Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae

Federica ORTELLI, Louise C. ROSSITER, John VONTAS, Hilary RANSON, Janet HEMINGWAY
Journal: Biochemical Journal
Biochem J (2003) 373 (3): 957–963.
https://doi.org/10.1042/bj20030169
Published: 01 August 2003
...Federica ORTELLI; Louise C. ROSSITER; John VONTAS; Hilary RANSON; Janet HEMINGWAY A cluster of eight genes encoding glutathione transferases (GSTs) are located on division 33B of polytene chromosome arm 3R of the African malaria mosquito, Anopheles gambiae . This region of the genome contains...
View article titled, Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae
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