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Keywords: myriocin
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Articles
Journal:
Biochemical Journal
Biochem J (2009) 417 (3): 791–801.
Published: 16 January 2009
... (small-hairpin RNA) or sustained incubation with myriocin, an SPT inhibitor. Incubation of L6 myotubes with palmitate (for 16 h) increases intramyocellular ceramide and reduces insulin-stimulated PKB activation and glucose uptake. PKB inhibition was not associated with impaired IRS (insulin receptor...
Includes: Supplementary data
Articles
Michiko MOMOI, Daisuke TANOUE, Yidi SUN, Hiromu TAKEMATSU, Yusuke SUZUKI, Minoru SUZUKI, Akemi SUZUKI, Tetsuro FUJITA, Yasunori KOZUTSUMI
Journal:
Biochemical Journal
Biochem J (2004) 381 (1): 321–328.
Published: 22 June 2004
...Michiko MOMOI; Daisuke TANOUE; Yidi SUN; Hiromu TAKEMATSU; Yusuke SUZUKI; Minoru SUZUKI; Akemi SUZUKI; Tetsuro FUJITA; Yasunori KOZUTSUMI ISP-1 (myriocin) is a potent inhibitor of serine palmitoyltransferase, the primary enzyme of sphingolipid biosynthesis, and is a useful tool for studying...