... The Biochemical Society, London ©2003 2003 conformational epitope metal ion neurodegenerative Abbreviations used: ARR, disease-resistant allelic form A 136 R 154 R 171 ; BSE, bovine spongiform encephalopathy; CJD, Creutzfeldt—Jakob disease; ECL, enhanced chemiluminescence; PBS-T20, PBS...

... and multiple sclerosis. These actions have been explained by the ability of the Mn-Salen to remove deleterious superoxide (O 2 − ) and H 2 O 2 . However, in addition to oxidative stress, cells in models for neurodegenerative diseases may also be subjected to damage from reactive nitrogen oxides (nitrosative...