...Elena M. Ribe; Ying Y. Jean; Rebecca L. Goldstein; Claudia Manzl; Leonidas Stefanis; Andreas Villunger; Carol M. Troy Caspase 2 was initially identified as a neuronally expressed developmentally down-regulated gene (HUGO gene nomenclature CASP2 ) and has been shown to be required for neuronal death...

... (amyloid β precursor protein) or a PS (presenilin) mutant, but not that of wild-type APP or PS, induced neuronal death by activating intracellular death signals, it remains to be addressed how these signals are interrelated and what the key molecule involved in this process is. In the present study, we...