... by interfering in host blood clotting and purinergic signaling pathways [ 6 ]. The present study focuses on two additional ectoenzymes that are both known to cleave nicotinamide adenine dinucleotide (NAD) [ 7 , 19–21 ]. These are the pyrophosphatase/phosphodiesterase, SmNPP5, and the glycohydrolase, SmNACE...

... electron provider and ascorbate, glutathione or possibly NAD(P)H itself as final reducing agent. Key words: chelatable iron, ferrous iron, nicotinamide adenine dinucleotide, reactive oxygen species, redox state. recent studies show that a rise in the chelatable iron pool itself can be the cause of cell...