... B have been deposited in the PDB under code 4JS9. 29 10 2014 23 12 2014 22 1 2015 22 1 2015 © The Authors Journal compilation © 2015 Biochemical Society 2015 Nitric oxide synthases (NOSs) are haem-thiolate enzymes that catalyse the conversion of L -arginine ( L...

... dimethylaminohydrolase 1), an enzyme that metabolizes endogenously produced nitric oxide synthase inhibitors, principally ADMA (asymmetric dimethylarginine). The present study employs a series of rodent models to evaluate the effectiveness a DDAH1-selective inhibitor (L-257). Short-term models involved the development...

... pathways mediating the effects of VEGF 165 on eNOS (endothelial nitric oxide synthase) activation. Despite equal expression levels of VEGFR-1 and VEGFR-2 in UAECs (uterine artery endothelial cells) from NP (non-pregnant) and P (pregnant) sheep, VEGF 165 activates eNOS at a greater level in P- compared...

....de ). 24 2 2006 31 3 2006 12 4 2006 The Biochemical Society, London 2006 acylation cycle differential activation intracellular trafficking nitric oxide synthase protein–protein interaction subcellular targeting Small and swift, but certainly not soft...

.... Immunolocalization of inducible nitric oxide synthase in synovium and cartilage in rheumatoid arthritis and osteoarthritis Br. J. Rheumatol. 1997 36 651 655 9 Presle N. Cipolletta C. Jouzeau J. Y. Abid A. Netter P. Terlain B. Cartilage protection by nitric oxide synthase...

...Kennedy MAKONDO; Kazuhiro KIMURA; Naoki KITAMURA; Takanori KITAMURA; Daisuke YAMAJI; Bae Dong JUNG; Masayuki SAITO Hepatocyte growth factor (HGF) causes endothelium-dependent vasodilation, but its relation to endothelial nitric oxide synthase (eNOS) activity remains to be elucidated. Treatment...

... of cells with anti-TfR antibody (IgA class) inhibited MPP + -induced caspase activation. Inhibition of nitric oxide synthase activity did not affect caspase 3 activity, apoptotic cell death or ROS generation by MPP + . Overall, these results suggest that MPP + -induced cell death in CGNs and neuroblastoma...

...-capacitative Ca 2+ entry ; NOC-18, 2,2«- (hydroxynitrosohydrazino)bis-ethanamine; NOS, nitric oxide synthase; ODQ, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; PKG, protein kinase G; RHC-80267, 1,6-bis(cyclohexyloximinocarbonylamino)hexane; U73122, 1-[6((17b-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-1H...

[email protected] ). 22 10 2001 8 1 2002 7 3 2002 The Biochemical Society, London ©2002 2002 acute renal failure GPI-specific phospholipase C nitric oxide synthase renal dipeptidase Abbreviations used: CRD, cross-reacting determinant; GPI, glycosylphosphatidylinositol; GPI...

... in brain iron together with a decrease in the Abbreviations used: NGF, nerve growth factor ; nNOS, neuronal nitric oxide synthase; NTA, nitrilotriacetate ; NTBI, non-transferrin-bound iron; PSS, physiological saline solution; TBI, transferrin-bound iron. 1 To whom correspondence should be addressed (e...

... by considering NOd as a physiological regulator of cell respiration and ATP production in isolated mitochondria [6 8] and intact cells [9]. This modulation of respiration has been attributed to the production of NOd by a mitochondrial nitric oxide synthase (NOS) [6 8,10] immunolocalized in these organelles [11...

..., these compounds discriminate among calmodulin-binding motifs. 1 To whom correspondence should be addressed (e-mail [email protected] ). 13 11 2000 11 1 2001 16 2 2001 The Biochemical Society, London © 2001 2001 dimer G-protein nitric oxide synthase ryanodine...