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Keywords: non-coding RNA
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Biochem J (2024) 481 (12): 793–804.
Published: 17 June 2024
... endonucleases immunology non-coding RNA CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR associated proteins) systems provide anti-viral adaptive immunity in prokaryotes, capable of memorising past invasions and targeting the same invading nucleic acids upon future...
Includes: Supplementary data
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Biochem J (2019) 476 (8): 1227–1245.
Published: 26 April 2019
... of these modifications in the coding and non-coding RNA species. Across all organisms, transfer RNAs (tRNAs) undergo the most diverse chemical modifications as part of their maturation and function. Many unique modifications have only been described in the context of tRNA and ribosomal RNA (rRNA), both of which have...
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Biochem J (2017) 474 (24): 4219–4251.
Published: 14 December 2017
...Ondrej Slaby; Richard Laga; Ondrej Sedlacek The majority of the human genome encodes RNAs that do not code for proteins. These non-coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and tumour suppressive genes, which make them a new class of targets for drug...