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Keywords: noradrenochrome
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Nyssa Drinkwater, Christine L. Gee, Munish Puri, Kevin R. Criscione, Michael J. McLeish, Gary L. Grunewald, Jennifer L. Martin
Journal:
Biochemical Journal
Biochem J (2009) 422 (3): 463–471.
Published: 27 August 2009
... illustrate the adaptability of the PNMT substrate binding site in accepting multi-fused ring systems, such as substituted norbornene, as well as noradrenochrome, the oxidation product of noradrenaline. These results explain why only a subset of ligands recognized by PNMT are methylated by the enzyme; bulky...
Includes: Supplementary data
