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Keywords: nuclear factor κB
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Articles
Biochem J (2021) 478 (13): 2619–2664.
Published: 16 July 2021
...Jack A. Prescott; Jennifer P. Mitchell; Simon J. Cook Cells must adapt to changes in their environment to maintain cell, tissue and organismal integrity in the face of mechanical, chemical or microbiological stress. Nuclear factor-κB (NF-κB) is one of the most important transcription factors that...
Articles
Biochem J (2021) 478 (3): 533–551.
Published: 10 February 2021
... was enabled by the participation of University of Liverpool in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. DNA damage response nuclear factor κB phosphorylation/dephosphorylation proteomics...
Includes: Supplementary data
Articles
Biochem J (2007) 406 (2): 215–221.
Published: 13 August 2007
...) and Bcl-2 protein expression. Additionally, morphine was found to suppress DOX-induced NF-κB (nuclear factor κB) transcriptional activation via a reduction of IκBα (inhibitor of nuclear factor κB) degradation. These present findings support the hypothesis that morphine can inhibit DOX-induced...
Articles
Biochem J (2005) 389 (1): 83–89.
Published: 21 June 2005
... transition), alterations in calcium homoeostasis and transcription factor activation. Of these, only the transcription factor NF-κB (nuclear factor κB) was implicated. TNF caused maximal nuclear translocation of NF-κB within 15 min, compared with 1 h in cells pretreated with MitoVit E. Thus the accumulation...
Articles
Biochem J (2003) 370 (2): 459–467.
Published: 01 March 2003
... inhibitors PD98059 and U0126. Supplementation of BV-2 cells with αTocH before LPS stimulation resulted in pronounced up-regulation of protein phosphatase 2A (PP2A) activity, down-regulation of PKC activity, ERK1/2 phosphorylation and nuclear factor κB (NFκB) activation. As a result, COX-2 protein levels and...
Articles
Biochem J (2001) 357 (3): 617–623.
Published: 25 July 2001
...Paul C. EVANS; Ellen R. TAYLOR; John COADWELL; Karen HEYNINCK; Rudi BEYAERT; Peter J. KILSHAW The transcription factor nuclear factor κB (NF-κB) plays a pivotal role in inflammatory processes through induction of adhesion molecules and chemokines. The zinc finger molecule A20 is an important...
Articles
Biochem J (2001) 354 (2): 351–358.
Published: 22 February 2001
...-transcriptase-mediated PCR respectively. The activation of nuclear factor κB (NF-κB) was investigated by electrophoretic mobility-shift assay. TG (100nM) induced a marked synthesis of iNOS mRNA, iNOS protein and NO in cells primed with a low concentration of endotoxin [lipopolysaccharide (LPS) 1ng/ml], which on...
Articles
Biochem J (2001) 353 (2): 275–281.
Published: 08 January 2001
... inhibitor of nuclear factor κB (‘IκB’), although no activation of extracellular signal-regulated protein kinase (ERK) (p42/44 MAPK) was observed. The use of antibodies against specific JNK isoforms showed that, in liver, short (p46) JNK1 and long (p54) JNK2 are the predominant forms activated, with smaller...
Articles
Biochem J (2000) 351 (3): 661–668.
Published: 24 October 2000
... nuclear factor κB promoter Sp1 Biochem. J. (2000) 351, 661 668 (Printed in Great Britain) 661 Characterization of the mouse dynamin I gene promoter and identification of sequences that direct expression in neuronal cells Jiyun YOO*, Sang Seop LEE*, Moon-Jin JEONG*, Kyung Im LEE*, Byoung-Mog KWON...
Articles
Biochem J (2000) 348 (3): 585–590.
Published: 07 June 2000
... TATA-binding protein 1 nuclear factor κB transcription Biochem. J. (2000) 348, 585 590 (Printed in Great Britain) 585 A new method for the selection of protein interactions in mammalian cells Eileen ROJO-NIERSBACH, Debra MORLEY, Stephanie HECK, and Norbert LEHMING1 Max-Delbru$ ck-Laboratorium in...